Circulation:非O型血的人静脉和动脉血栓事件的发生率较高

2016-03-07 MedSci MedSci原创

ABO血型已显示出能够增加静脉血栓栓塞和动脉疾病的风险。然而,该联系的报告的幅度并不一致,并且只是基于小型研究的证据。研究人员使用献血者的SCANDAT2数据库与其他全国性的健康数据寄存器链接调查了ABO血型和复发性静脉血栓和动脉事件的发生率之间的关联。在1987年和2012年间丹麦和瑞典的献血者中,研究人员随访了血栓和动脉事件的诊断。泊松回归模型被用于估计发病率比(IRR)作为相对风险的措施。在

ABO血型已显示出能够增加静脉血栓栓塞和动脉疾病的风险。然而,该联系的报告的幅度并不一致,并且只是基于小型研究的证据。

研究人员使用献血者的SCANDAT2数据库与其他全国性的健康数据寄存器链接调查了ABO血型和复发性静脉血栓和动脉事件的发生率之间的关联。在1987年和2012年间丹麦和瑞典的献血者中,研究人员随访了血栓和动脉事件的诊断。泊松回归模型被用于估计发病率比(IRR)作为相对风险的措施。在1360万人年的的随访过程中,共有9,170例静脉和24653例动脉事件发生在1112072人中。相对于O型血,非O型血的静脉和动脉血栓事件的发生率较高。妊娠相关静脉血栓栓塞[IRR 2.22;95%置信区间(CI,1.77-2.79),深静脉血栓形成(IRR1.92; 95%CI,1.80-2.05),和肺栓塞(IRR1.80; 95%CI,1.71-1.88)的发生率最高。

在献血这种健康人群,非O型血参与者的静脉血栓栓塞事件达到30%以上。虽然ABO血型可以潜在地提供预测系统来用于识别风险个体,但其临床效用还需要与其它风险标志物进一步比较。

原始出处:

Vasan SK,Rostgaard K,Majeed A,et al.ABO Blood Group and Risk of Thromboembolic and Arterial Disease,Circulation,2016.3.3

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    2016-06-20 fusion
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  8. [GetPortalCommentsPageByObjectIdResponse(id=1697299, encodeId=3d98169e29960, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0bc129907796, createdName=fusion, createdTime=Mon Jun 20 10:31:00 CST 2016, time=2016-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1946068, encodeId=d4d9194606810, content=<a href='/topic/show?id=1737890867a' target=_blank style='color:#2F92EE;'>#血栓事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89086, encryptionId=1737890867a, topicName=血栓事件)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4736501, createdName=xiaoyang_ambs, createdTime=Mon Dec 26 20:31:00 CST 2016, time=2016-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1708955, encodeId=467a1e0895535, content=<a href='/topic/show?id=1502333250f' target=_blank style='color:#2F92EE;'>#动脉血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33325, encryptionId=1502333250f, topicName=动脉血)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=048f31575940, createdName=ms9833124466084992, createdTime=Thu Oct 20 02:31:00 CST 2016, time=2016-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826307, encodeId=7d39182630e94, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Fri Jul 01 07:31:00 CST 2016, time=2016-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1536807, encodeId=6851153680e18, content=<a href='/topic/show?id=fcbd3332949' target=_blank style='color:#2F92EE;'>#动脉血栓#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33329, encryptionId=fcbd3332949, topicName=动脉血栓)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=715e12724163, createdName=yangcx0919, createdTime=Tue Mar 08 22:31:00 CST 2016, time=2016-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1558430, encodeId=6f78155843098, content=<a href='/topic/show?id=99ea135e8fa' target=_blank style='color:#2F92EE;'>#O型血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13578, encryptionId=99ea135e8fa, topicName=O型血)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a16e14977467, createdName=doctor-chen9587, createdTime=Tue Mar 08 22:31:00 CST 2016, time=2016-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1564439, encodeId=afe015644390a, content=<a href='/topic/show?id=99ea135e8fa' target=_blank style='color:#2F92EE;'>#O型血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13578, encryptionId=99ea135e8fa, topicName=O型血)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a16e14977467, createdName=doctor-chen9587, createdTime=Tue Mar 08 22:31:00 CST 2016, time=2016-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=67729, encodeId=05416e7297e, content=很好,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Mar 07 08:53:00 CST 2016, time=2016-03-07, status=1, ipAttribution=)]
    2016-03-07 dhzzm

    很好,学习了!

    0