Eur Neurol:脑室周围白质高信号可预测其边缘梗死

2015-12-21 phylis 译 MedSci原创

背景:白质高信号(WMH)预测卒中和新的腔隙性梗死的发生;此外,WMH也影响梗死部位。这篇研究旨在确定WMH和急性腔隙性脑梗死之间的空间关系。方法:共有590名幕上区急性腔隙性梗死的患者。进行轴位和冠状位MRI评估梗死和WMH的四种情况:与WMH无接触(0级),接触不重叠(Ia级),部分重叠(Ib级)和完全重叠(II级)。此外,研究者定义Ia级,Ib级梗死定义为边缘部位梗死,并且调查其预测因子极其

背景:白质高信号(WMH)预测卒中和新的腔隙性梗死的发生;此外,WMH也影响梗死部位。这篇研究旨在确定WMH和急性腔隙性脑梗死之间的空间关系。

方法:共有590名幕上急性腔隙性脑梗死的患者。进行轴位和冠状位MRI评估梗死和WMH的四种情况:与WMH无接触(0级)、接触不重叠(Ia级)、部分重叠(Ib级)和完全重叠(II级)。此外,研究者定义Ia级,Ib级梗死定义为边缘部位梗死,并且调查其预测因子极其短期预后。

结果:47.9%(283)的患者为Ia级和Ib级(Ia级= 27.6%,IB级= 20.3%);51.5%(304)名为0级;只有0.5%(3)为II级。与非边缘梗死患者相比,边缘梗死患者的入院梗死面积较大,WMH较严重,NHISS分数较高,BI分数较低。边缘梗死患者出院分数也较低。皮质下白质梗死,弥散加权成像面积,脑室周围WMH及深部WMH是边缘梗死的预测因子。

结论:半数腔隙性脑梗死位于WMH边缘。脑室周围WMH和深部WMH是边缘局部梗死的预测因子。

原文出处:

Zhang X, Ding L, et al.  Spatial Relationship between Acute Lacunar Infarction and White Matter Hyperintensities. Eur Neurol.2015 Dec 9.


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    2016-01-10 docwu2019
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    2015-12-26 hixiaoluo

    值得收藏,学习,谢谢分享

    0

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    2015-12-23 tastas

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