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Eur Heart J:高敏心肌肌钙蛋白T预测远期死亡更佳

2013-07-10 高晓方 译 cmt

高敏心肌肌钙蛋白T远期死亡
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欧洲一项研究表明，高敏心肌肌钙蛋白T（hs-cTnT）预测远期死亡的准确性优于高敏心肌肌钙蛋白I（hs-cTnI）。论文7月2日在线发表于《欧洲心脏杂志》（Eur Heart J）。 此项研究共纳入1117例非选择性急性胸痛患者，并以设盲方式同时采用三种新型方法和一种传统方法测定心肌肌钙蛋白。就死亡状况对患者进行为期2年的随访。随访期间共有82例（7.3%）患者死亡。

欧洲一项研究表明，高敏心肌肌钙蛋白T（hs-cTnT）预测远期死亡的准确性优于高敏心肌肌钙蛋白I（hs-cTnI）。论文7月2日在线发表于《欧洲心脏杂志》（Eur Heart J）。

此项研究共纳入1117例非选择性急性胸痛患者，并以设盲方式同时采用三种新型方法和一种传统方法测定心肌肌钙蛋白。就死亡状况对患者进行为期2年的随访。随访期间共有82例（7.3%）患者死亡。

结果显示，hs-cTnT的2年预测准确性最高（AUC 0.78），并且优于hs-cTnI和心肌肌钙蛋白T（cTnT）。在预测死亡率方面方面，hs-cTnT绝对变化预测死亡的准确性优于hs-cTnT相对变化，但不如hs-cTnT现值。6小时内hs-cTnT变化与现值联合未能进一步改善预测准确性。在既存冠脉疾病、肾功能受损和年龄>75岁等具有临床预测难度的亚组患者中，hs-cTn浓度仍为死亡预测因素。


Risk stratification in patients with acute chest pain using three high-sensitivity cardiac troponin assays  

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    2013-07-17 dzx0922889

    #高敏心肌肌钙蛋白#

    0

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    2014-01-20 yanjie6253_56072853

    #高敏心肌肌钙蛋白T#

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    2013-07-12 zhaojie88

    #ART#

    0

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    2013-07-12 wrj0124

    #心肌肌钙蛋白#

    0

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    2013-07-12 slcumt

    #HEART#

    0

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    2013-07-12 huangdf

    #肌钙蛋白T#

    0

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    2013-07-10 Susan0806

    有帮助

    0