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AJC：non-HDL-C是冠状动脉钙化进展的更佳预测因素

2014-04-21 寒林 译 医学论坛网

胆固醇non-HDL-C动脉粥样硬化预测因素
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美国一项研究表明，非高密度脂蛋白胆固醇(non-HDL-C)水平，尤其是>190 mg/dl时，与动脉粥样硬化(AS)患者的冠状动脉钙化(CAC)进展风险增加相关。这个研究揭示，在血浆脂类指标中，也许非高密度脂蛋白胆固醇(non-HDL-C)水平可以作为预测AS患者CAC进展的最适因素，该研究在线发表在《美国心脏病学杂志》(Am J Cardiol)。 研究共分析了5705例AS患者，结果

美国一项研究表明，非高密度脂蛋白胆固醇(non-HDL-C)水平，尤其是>190 mg/dl时，与动脉粥样硬化(AS)患者的冠状动脉钙化(CAC)进展风险增加相关。这个研究揭示，在血浆脂类指标中，也许非高密度脂蛋白胆固醇(non-HDL-C)水平可以作为预测AS患者CAC进展的最适因素，该研究在线发表在《美国心脏病学杂志》(Am J Cardiol)。

研究共分析了5705例AS患者，结果显示，在校正年龄、性别、种族、动脉收缩压、抗高血压药物使用、吸烟、糖尿病、降脂治疗、随访时长和腰臀比后，对于基线无CAC的患者，non-HDL-C(特别是>190 mg/dl时)与CAC发生危险独立相关[相对危险(RR)=1.40，95%可信区间(CI)为1.09~1.79，P=0.008]。同样，对于基线即存在CAC的患者，non-HDL-C>190 mg/dl与CAC显著进展相关(RR=16.4，95%CI为-5.63~27.2，P=0.003)。

原始出处：


Zalawadiya SK1, Veeranna V1, Panaich S1, Kottam A1, Afonso L2.Non-high-density lipoprotein cholesterol and coronary artery calcium progression in a multiethnic US population.Am J Cardiol. 2014 Feb 1;113(3):471-4. doi: 10.1016/j.amjcard.2013.10.027. Epub 2013 Nov 9.

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    2015-02-18 lhlxtx

    #non-HDL-C#

    0

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    2015-01-20 1249897bm45(暂无昵称)

    #动脉钙化#

    0

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    2015-02-23 夏天与十三菇凉

    #冠状动脉钙#

    0

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    2014-04-23 朱睿睿

    #预测因素#

    0

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    2014-04-23 shizhenshan

    #冠状动脉钙化#

    0

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    2014-04-23 ZGMFX24A

    #HDL#

    0

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    2014-04-23 ms920641618706883

    #HDL-C#

    0

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