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Eur Heart J：他汀一级预防显著减少医疗资源应用

2013-07-15 高晓方 译 cmt

医疗保健资源他汀一级预防
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英国一项研究表明，中年男性长期接受普伐他汀一级预防可显著减少医疗保健资源应用，节省相关费用，并增加质量校正生命年（QALY）。论文7月9日在线发表于《欧洲心脏杂志》（Eur Heart J）。 此项研究共纳入6595例年龄为45～54岁的男性受试者，并随机给予5年的普伐他汀（40 mg）或安慰剂治疗。对医疗保健资源应用情况进行为期15年的扩展随访。报告指标为

英国一项研究表明，中年男性长期接受普伐他汀一级预防可显著减少医疗保健资源应用，节省相关费用，并增加质量校正生命年（QALY）。论文7月9日在线发表于《欧洲心脏杂志》（Eur Heart J）。

此项研究共纳入6595例年龄为45～54岁的男性受试者，并随机给予5年的普伐他汀（40 mg）或安慰剂治疗。对医疗保健资源应用情况进行为期15年的扩展随访。报告指标为包括心梗、心衰、卒中、冠脉血运重建和血管造影在内的病因特异性首次和复发心血管住院，以及非心血管住院、住院时间、QALY和治疗费用等。

结果显示，1000例患者为期5年的普伐他汀治疗节省了710000英镑医疗保健费用，并在15年期间获得136 QALY（P=0.017）。归因于心血管事件预防的每1000例受试者获益包括减少163例次入院，省去1836天住院时间，以及减少心梗、卒中、心衰和冠脉血运重建住院。随访期间无超额非心血管住院或超额费用，并且未发现亚组受试者的异质性影响证据。


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  1. [GetPortalCommentsPageByObjectIdResponse(id=1346898, encodeId=80f0134689876, content=<a href='/topic/show?id=a252351803c' target=_blank style='color:#2F92EE;'>#医疗资源#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35180, encryptionId=a252351803c, topicName=医疗资源)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93e223, createdName=bluefate121, createdTime=Wed Jul 17 08:47:00 CST 2013, time=2013-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355779, encodeId=41b41355e7945, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Jul 17 08:47:00 CST 2013, time=2013-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562176, encodeId=6d8815621e67b, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Jul 17 08:47:00 CST 2013, time=2013-07-17, status=1, ipAttribution=)]
    2013-07-17 bluefate121

    #医疗资源#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1346898, encodeId=80f0134689876, content=<a href='/topic/show?id=a252351803c' target=_blank style='color:#2F92EE;'>#医疗资源#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35180, encryptionId=a252351803c, topicName=医疗资源)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93e223, createdName=bluefate121, createdTime=Wed Jul 17 08:47:00 CST 2013, time=2013-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355779, encodeId=41b41355e7945, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Jul 17 08:47:00 CST 2013, time=2013-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562176, encodeId=6d8815621e67b, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Jul 17 08:47:00 CST 2013, time=2013-07-17, status=1, ipAttribution=)]
    2013-07-17 zhaojie88

    #ART#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1346898, encodeId=80f0134689876, content=<a href='/topic/show?id=a252351803c' target=_blank style='color:#2F92EE;'>#医疗资源#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35180, encryptionId=a252351803c, topicName=医疗资源)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93e223, createdName=bluefate121, createdTime=Wed Jul 17 08:47:00 CST 2013, time=2013-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355779, encodeId=41b41355e7945, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Jul 17 08:47:00 CST 2013, time=2013-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562176, encodeId=6d8815621e67b, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Jul 17 08:47:00 CST 2013, time=2013-07-17, status=1, ipAttribution=)]
    2013-07-17 slcumt

    #HEART#

    0