生姜可以改善心脏功能,提高心肺复苏后的存活率

2015-11-08 zhaoshuang 译 MedSci原创

两位动物研究者发表在美国心脏协会2015年科学会议上的一项研究表明,生姜中的活性成分姜黄素对心肺复苏后的心脏有保护作用。在第一项实验中,他们将24只老鼠平均分成三组,第一组在心肺复苏后给予姜黄素和肾上腺素继续治疗,第二组仅给予肾上腺素治疗,第三组不给任何药物实验结果:1 肾上腺素/姜黄素联合治疗和肾上腺素组的老鼠全部存活了,而没有药物治疗的只有六只老鼠存活。2 肾上腺素/姜黄素联合治疗组有七只老鼠

两位动物研究者发表在美国心脏协会2015年科学会议上的一项研究表明,生姜中的活性成分姜黄素对心肺复苏后的心脏有保护作用。

在第一项实验中,他们将24只老鼠平均分成三组,第一组在心肺复苏后给予姜黄素和肾上腺素继续治疗,第二组仅给予肾上腺素治疗,第三组不给任何药物。

实验结果:

1 肾上腺素/姜黄素联合治疗和肾上腺素组的老鼠全部存活了,而没有药物治疗组的只有六只老鼠存活。

2 肾上腺素/姜黄素联合治疗组有七只老鼠的存活时间超过24小时,而肾上腺素组有2只,无药物治疗组有1只心肺复苏后存活时间超过24小时。

研究人员表明,肾上腺素既对机体有益,又对机体有害。在CPR过程中,肾上腺素会使四肢血管收缩,使回心血量增加,大脑供血量增加,

但是肾上腺素也增加了心脏对氧气的需求。由于在CPR过程中无法满足充足的含氧量,因此会对机体造成损害。

他们提出,只接受肾上腺素治疗对心脏功能损害最大,而肾上腺素/姜黄素联合治疗对心脏损害作用最小,表明姜黄素可以预防肾上腺素对心脏功能的损害。

在类似的研究中,将16只老鼠被分为两组,实验组在实验初期,根据体重给予450-550g的姜黄素喂养,对照组组则不给于姜黄素。

在诱导老鼠心律不齐八分钟后对其进行心肺复苏和除颤使其恢复正常心律。

实验结果:

1 姜黄素喂养组有7只老鼠复苏成功,对照组有6只复苏成功。

2 超声波测试发现16只老鼠的心肌均受到重大损害。

3 实验组的老鼠复苏成功后心脏功能更好。

原始出处:


AMERICAN HEART ASSOCIATION NEWS .Spice improves heart function, survival after CPR.November 8th, 2015

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    2016-01-22 aids222
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    2016-01-23 wei834766788

    看看

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    2015-11-10 dhzzm

    值得学习,有机会会在实际工作中试用。

    0

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    2015-11-10 lizhou0204
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