JAMA Psychiatry:电休克治疗与精神病再住院风险研究

2017-06-29 zhangfan MedSci原创

电休克治疗可减少严重的情感障碍患者短期精神病再住院率


研究人员对全美9个州医院精神疾病再入院数据进行准实验的工具变量概率模型分析,包含490252名入院精神疾病患者,其中162691名重度抑郁症、双相情感障碍以及分裂情感障碍患者。研究包括人口亚群, ECT年龄、性别,种族和诊断组等异质性因素对于ECT和再入院的影响。

总计2486名患者进行了ECT治疗,相比于其他患者,接受ECT治疗患者的年龄更大(56.8岁vs45.9岁),女性比例高(65.0% vs 54.2%)且非西班牙裔白人比例大(85.3% vs 62.1%), ECT治疗患者患重度抑郁症比例较高(63.8% vs 32.0%; P<0.001),双相障碍(29.0% vs 40.0%; P<0.001) 以及情感分裂性精神障碍(7.1% vs 28.0%; P<0.001)比例低,存在共存性疾病(31.3% vs 26.6%; P<0.001),有私人(39.4% vs 21.7%; P<0.001)或医疗保险(49.2% vs 39.4%; P<0.001)比例高,城市小型医疗机构(31.2% vs 22.3%; P<0.001)以及乡村医院(9.0% vs 7.6%; P=0.02).患者比例高。接受ECT治疗可降低严重情感障碍患者30天再入院率,接受ECT患者再入院率为6.6%,未接受患者为12.3%(RR,0.54,95% CI,0.28-0.81),其中男性患者是否接受ECT对再入院率的影响超过女性患者(RR,0.44;95% CI,0.20-0.69 vs 0.58;95% CI,0.30-0.88)。相比于严重抑郁(RR,0.53;95% CI,0.26-0.81)患者,双相障碍(RR,0.42;95% CI,0.17-0.69)以及情感分裂性精神障碍(RR,0.44;95% CI,0.11-0.79)受ECT影响较大。

电休克治疗可减少严重的情感障碍患者短期精神病再住院率。

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    2017-06-29 131****1460

    学习了受益匪浅。

    0

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    2017-06-29 三生有幸9135

    学习一下谢谢分享

    0

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