Clin Gastroenterology H: 减肥手术后青少年的营养风险评估

2020-05-01 MedSci原创 MedSci原创

目前关于代谢减肥手术后青少年营养缺乏症的患病率和危险因素知之甚少。本项研究旨在对这些患者进行为期5年的前瞻性队列研究。

背景与目标: 目前关于代谢减肥手术后青少年营养缺乏症的患病率和危险因素知之甚少。本项研究旨在对这些患者进行为期5年的前瞻性队列研究。

方法: 研究人员在2007年3月至2012年2月间,将在5个三级医疗中心接受了Roux-en-Y胃旁路手术(RYGB,n = 161)或垂直袖胃切除术(VSG,n = 67)的青少年纳入本项研究。最终的分析队列包括226名参与者(161人使用RYGB,65人使用VSG)。研究人员测量了他们的血清铁蛋白水平。红细胞叶酸; 维生素A,D,B 1和B 12;基线和每年5年甲状旁腺激素水平。一般线性混合模型用于检查随时间的变化并确定与营养缺乏相关的因素。

结果: 参与者中女性占75%,白人占72%,平均年龄为16.5±1.6岁,手术时的平均体重指数为52.7±9.4 kg/m2。平均体重指数在5年时降低了23%,并且两次手术之间无显着差异。RYGB治疗后,血清维生素B12浓度显着下降,而转铁蛋白和甲状旁腺激素的血清水平升高。两种手术方法后铁蛋白水平均显着下降。叶酸或维生素A,B1的血清水平无明显变化。到5年时,59%的RYGB和27%的VSG接受者均出现营养缺乏的症状。

结论: 在本项研究中研究人员发现青少年减肥手术术后5年的会营养缺乏症,尤其是RYGB术后铁和B12的营养缺乏症。建议对所有患者进行持续的营养监测和补充,但是手术类型,补充摄入量,性别和种族可能会影响风险。

原始出处:

Stavra A. Xanthakos. Nutritional Risks in Adolescents After Bariatric Surgery. Clin Gastroenterology H.2020.

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    2020-10-18 许安
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    2020-05-01 CHANGE

    什么时候有懒人用的减肥神药?

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