Crit Care Med:酒精相关性肝病ICU患者的长期死亡率和医院资源使用情况分析

2018-09-23 xing.T MedSci原创

由此可见,酒精相关的肝病的ICU患者5年死亡率和紧急再入院率高于其他严重合并症的ICU患者以及匹配的一般ICU患者。这些数据有助于酒精相关肝病患者的共同决策。

描述ICU治疗酒精相关性肝病患者的长期结果的数据很少。近日,危重病医学领域权威杂志Critical Care Medicine上发表了一篇研究文章,研究人员旨在报告酒精相关性肝病患者的长期死亡率和急诊医院资源使用情况,并将其与两个对照队列进行比较。

该研究为链接人口登记数据的回顾性队列研究,以所有苏格兰成年普通ICU(2005-2010)提供服务的500万人群为基础。研究人员将患有酒精相关性肝病的ICU患者与进行急性生理学和慢性健康评估,定义为严重血管、呼吸或肾脏合并症诊断的的未配对队列和匹配的一般ICU队列进行比较。该研究的结局为5年死亡率、医院急诊资源使用和紧急再入院。多变量回归用于识别危险因素并调整混杂因素。

在47779例入住ICU的患者中,研究人员确定了2463例酒精相关性肝病患者和3590例严重合并症患者; 2391例(97.1%)患者与一般ICU队列匹配。与酒精相关的肝病患者队列的5年死亡率高于合并症患者(79.2% vs. 75.3%; p<0.001)和匹配的一般队列(79.8% vs. 63.3%; p<0.001)。较高的肝脏序贯器官衰竭评估评分和三器官支持与酒精相关肝病患者的5年死亡率90%相关。调整混杂因素后,与酒精相关的肝病患者死亡风险增加31%(校正风险比为1.31; 95%CI为1.17-1.47; p<0.001),并且使用的资源比严重的合并症对照组要高。与匹配的队列相比,结果相似。

由此可见,酒精相关的肝病的ICU患者5年死亡率和紧急再入院率高于其他严重合并症的ICU患者以及匹配的一般ICU患者。这些数据有助于酒精相关肝病患者的共同决策。

原始出处:

Lone, Nazir I.et al. Long-Term Mortality and Hospital Resource Use in ICU Patients With Alcohol-Related Liver Disease.critical care medicine.2018. https://journals.lww.com/ccmjournal/Abstract/onlinefirst/Long_Term_Mortality_and_Hospital_Resource_Use_in.96139.aspx

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    2018-09-24 lietome24

    认真学习,不断进步,把经验分享给同好。点赞了!

    0

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    2018-09-23 1e145228m78(暂无匿称)

    学习了,谢谢作者分享!

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2066149, encodeId=10ed2066149fa, content=<a href='/topic/show?id=abfc9549600' target=_blank style='color:#2F92EE;'>#酒精相关性肝病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95496, encryptionId=abfc9549600, topicName=酒精相关性肝病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b632500090, createdName=h.y200607_23674418, createdTime=Mon Jun 17 17:27:00 CST 2019, time=2019-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1837568, encodeId=ecc0183e568b2, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Fri May 03 13:27:00 CST 2019, time=2019-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1660827, encodeId=7a45166082e67, content=<a href='/topic/show?id=17b8268041b' target=_blank style='color:#2F92EE;'>#使用情况#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26804, encryptionId=17b8268041b, topicName=使用情况)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=169625169742, createdName=dzx0922897, createdTime=Thu Nov 29 21:27:00 CST 2018, time=2018-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1595370, encodeId=a32215953e004, content=<a href='/topic/show?id=44b993e977' target=_blank style='color:#2F92EE;'>#ICU患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9379, encryptionId=44b993e977, topicName=ICU患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=003c18235152, createdName=piaojinhua, createdTime=Tue Sep 25 00:27:00 CST 2018, time=2018-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609127, encodeId=22b1160912ea4, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue Sep 25 00:27:00 CST 2018, time=2018-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346430, encodeId=92cb346430d0, content=认真学习,不断进步,把经验分享给同好。点赞了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eb131638261, createdName=lietome24, createdTime=Mon Sep 24 11:50:36 CST 2018, time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346311, encodeId=062f34631133, content=学习了,谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Sun Sep 23 19:03:04 CST 2018, time=2018-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346275, encodeId=ef653462e58d, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Sun Sep 23 09:37:46 CST 2018, time=2018-09-23, status=1, ipAttribution=)]
    2018-09-23 医者仁心5538

    学习了

    0