山东学者报告,一种与血小板有关的因子可预测冠脉斑块稳定性

2017-07-22 朱柳媛 中国循环杂志

山东省东营市胜利油田中心医院于彩红报告,在冠心病患者中,血清血小板源性生长因子参与冠状动脉粥样硬化斑块的形成,斑块越不稳定,血清血小板源性生长因子浓度越高。

山东省东营市胜利油田中心医院于彩红报告,在冠心病患者中,血清血小板源性生长因子参与冠状动脉粥样硬化斑块的形成,斑块越不稳定,血清血小板源性生长因子浓度越高。

在该研究中,血管内超声检查显示,冠状动脉病变处硬斑块(纤维斑块、钙化斑块、混合斑块)的血清血小板源性生长因子水平均低于软斑块,而急性冠脉综合征患者的冠脉斑块以软斑块为主,而稳定性心绞痛患者斑块以硬斑块为主。

因此,作者认为,“检测血清血小板源性生长因子水平有助于诊断和预测急性冠脉综合征的发生,使急性冠脉综合征的诊断流程和治疗策略的选择更趋于合理和规范。”

研究者选取了行冠状动脉造影检查的106 例患者作为研究对象,其中急性冠状动脉综合征患者60 例,稳定性心绞痛患者46 例。

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    2017-07-27 wxl882001

    学习

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