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基于RNA-Seq的长非编码RNA（lncRNA）预测

2014-01-03 郭晓强,田占涛,李娜,段相林,王越甲 生物化学与生物物理学进展

RNA-Seq长非编码RNA
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随着新一代生物技术和生物信息学的发展，研究发现在真核生物转录组中存在大量长非编码RNA（long non-coding RNA, lncRNA），而这些lncRNA可能在基因表达调控过程中起到关键性的功能作用. 当前lncRNA研究主要采用高通量RNA-Seq测序技术，并通过生物信息学方法对测序数据进行处理和分析，以挖掘其中lncRNA的序列、结构、表达及功

随着新一代生物技术和生物信息学的发展，研究发现在真核生物转录组中存在大量长非编码RNA（long non-coding RNA, lncRNA），而这些lncRNA可能在基因表达调控过程中起到关键性的功能作用. 当前lncRNA研究主要采用高通量RNA-Seq测序技术，并通过生物信息学方法对测序数据进行处理和分析，以挖掘其中lncRNA的序列、结构、表达及功能等信息. 本文将对基于RNA-Seq的lncRNA预测流程进行介绍，对其中涉及的生物信息学方法进行较为全面的综述，就相关问题和挑战展开讨论，并对研究进行展望基于RNA_Seq的长非编码RNA预测_孙磊.pdf

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    2014-11-29 d830384

    #非编码#

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    2014-08-01 yanjie6253_56072842

    #CRN#

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    2014-01-05 xzw113

    #lncRNA#

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    2014-01-05 lixiaol

    #长非编码RNA#

    0

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    2014-01-05 lilianxiang

    #RNA-Seq#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1743413, encodeId=ba621e4341394, content=<a href='/topic/show?id=369199618db' target=_blank style='color:#2F92EE;'>#非编码#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99618, encryptionId=369199618db, topicName=非编码)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32d435134939, createdName=d830384, createdTime=Sat Nov 29 20:50:00 CST 2014, time=2014-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2005612, encodeId=d538200561233, content=<a href='/topic/show?id=6ff1525e13' target=_blank style='color:#2F92EE;'>#CRN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5257, encryptionId=6ff1525e13, topicName=CRN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=35fc2500023, createdName=yanjie6253_56072842, createdTime=Fri Aug 01 19:50:00 CST 2014, time=2014-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1301844, encodeId=f973130184414, content=<a href='/topic/show?id=b469109e41d' target=_blank style='color:#2F92EE;'>#lncRNA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10974, encryptionId=b469109e41d, topicName=lncRNA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2317301, createdName=xzw113, createdTime=Sun Jan 05 12:50:00 CST 2014, time=2014-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366082, encodeId=3f1513660824a, content=<a href='/topic/show?id=771f9e09207' target=_blank style='color:#2F92EE;'>#长非编码RNA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97092, encryptionId=771f9e09207, topicName=长非编码RNA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=920c231, createdName=lixiaol, createdTime=Sun Jan 05 12:50:00 CST 2014, time=2014-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1557685, encodeId=a48d155e6855d, content=<a href='/topic/show?id=9376155352a' target=_blank style='color:#2F92EE;'>#RNA-Seq#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15535, encryptionId=9376155352a, topicName=RNA-Seq)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=40e814925065, createdName=lilianxiang, createdTime=Sun Jan 05 12:50:00 CST 2014, time=2014-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1584617, encodeId=fadf158461e84, content=<a href='/topic/show?id=83f5e9250e9' target=_blank style='color:#2F92EE;'>#编码#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79250, encryptionId=83f5e9250e9, topicName=编码)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b10a17056098, createdName=12498f6em12暂无昵称, createdTime=Sun Jan 05 12:50:00 CST 2014, time=2014-01-05, status=1, ipAttribution=)]
    2014-01-05 12498f6em12暂无昵称

    #编码#

    0