BMJ:鸦片与抗抑郁类药物联合使用会增加过量服药的风险

2017-03-16 生物谷 生物谷

根据最近发表在BMJ杂志上的一篇文章,使用鸦片以及苯二氮平类药物(治疗焦虑以及睡眠问题)会导致过量摄入鸦片的风险增高。研究者们认为,对于同时使用苯二氮平类药物的患者来说,在开具使用鸦片止痛的处方时要十分小心,并且呼吁医生以及患者及早地重视这两种药物同时使用所带来的风险。在许多国家,处方药中过量开具鸦片导致了鸦片的过量摄入以及上瘾


根据最近发表在BMJ杂志上的一篇文章,使用鸦片以及苯二氮平类药物(治疗焦虑以及睡眠问题)会导致过量摄入鸦片的风险增高。

研究者们认为,对于同时使用苯二氮平类药物的患者来说,在开具使用鸦片止痛的处方时要十分小心,并且呼吁医生以及患者及早地重视这两种药物同时使用所带来的风险。

在许多国家,处方药中过量开具鸦片导致了鸦片的过量摄入以及上瘾的后果,这引发的全球健康问题变得越来越严重。

美国境内将近30%的鸦片摄入过量致死的患者同时服用苯二氮平类药物,这使得研究者们猜想鸦片引起的死亡或许与苯二氮平有关。

因此,来自加州的研究者们分析了目前患者使用鸦片以及苯二氮平类药物的具体情况。他们的研究囊括了超过30万明年龄在18-64岁之间的接受了鸦片治疗的患者。结果显示,早在2001年。其中9%的压片使用者同时接受了苯二氮平类药物的治疗,这一数字在2013年上升到了17%。

通过矫正其它因素的干扰之后,研究者们发现相比对照组群体,同时使用两组药物的患者鸦片上瘾的风险要高得多。

虽然这只是一个观察性的试验,并不能从中得到确切的因果关系,但如果其中的因果关系得到验证,那么将会有效降低患者压片使用过量或被迫急救的风险。

因此,研究者们建议,对于已经使用了苯二氮平类药物的患者而言,鸦片的使用应当十分小心,即使是对于短期的使用也应如此。

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    2017-04-02 gaoxiaoe
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    2017-03-16 shaosai

    好好学习,涨知识

    0

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    2017-03-16 1e15b6fem30(暂无匿称)

    很好的学习资料,谢谢了。

    0

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    2017-03-16 1de11f7fm56(暂无匿称)

    学习了,非常好的研究,谢谢分享

    0

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    2017-03-16 明月清辉

    谢谢分享,学习了

    0