内分泌科

订阅

MedSci主页 / 所有栏目 / 内分泌科

Diabetes:科学家从中药中发现治疗糖尿病肾病潜在药物

2011-11-13 MedSci原创 MedSci原创

糖尿病肾病糖尿病肉桂
关注

在最新一期(2011年11月号)美国糖尿病学会会刊《Diabetes》杂志上，刊登了第三军医大学新桥医院与美国亚利桑那大学药学院等单位联合完成的一项研究成果，该研究率先在国际上应用西兰花、肉桂中萃取的元素对糖尿病肾病进行干预，获得显著疗效。这一研究成果，为糖尿病肾病的临床治疗找到一个新的靶点。   该文第一作者、第三军医大学新桥医院内分泌科副主任郑宏庭博士与美国亚利桑那大学药学院 D

在最新一期(2011年11月号)美国糖尿病学会会刊《Diabetes》杂志上，刊登了第三军医大学新桥医院与美国亚利桑那大学药学院等单位联合完成的一项研究成果，该研究率先在国际上应用西兰花、肉桂中萃取的元素对糖尿病肾病进行干预，获得显著疗效。这一研究成果，为糖尿病肾病的临床治疗找到一个新的靶点。
 
该文第一作者、第三军医大学新桥医院内分泌科副主任郑宏庭博士与美国亚利桑那大学药学院 Donna Zhang课题组合作，通过小鼠体内实验和体外细胞模型的观察发现，从食物西兰花和中药材肉桂中提取的莱菔硫烷与肉桂醛这两种物质，可以减弱常见的糖代谢紊乱症状，改善糖尿病引致的糖代谢紊乱与肾损伤，从而为临床糖尿病肾病的治疗探索了一条新的路径。该研究工作得到了国家自然科学基金的资助。
 
另据了解，美国糖尿病学会会刊《糖尿病》杂志还配发了由国际著名糖尿病研究学者、澳大利亚Baker IDI心脏糖尿病研究中心Judy B.Haan教授所撰写的专文述评。
 
Haan教授在这篇述评中指出，糖尿病肾病是糖尿病常见的并发症，也是糖尿病患者死亡的主要原因之一。在美国，糖尿病肾病占终末期肾功能衰竭的首位，约为35%至38%。尽管目前临床依靠强化的代谢控制及其他一些干预措施试图延缓其进展，但随着肾功能无情地衰减，许多患者仍不可避免地步入肾衰阶段，这种现状导致了对新治疗手段的迫切需要。而郑宏庭博士他们的研究有望为糖尿病肾病的治疗提供一条全新的途径。（来源：中新网）

版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1900917, encodeId=9ee0190091e93, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Fri Oct 05 07:59:00 CST 2012, time=2012-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1923680, encodeId=91211923680bb, content=<a href='/topic/show?id=bf0a66e12f4' target=_blank style='color:#2F92EE;'>#潜在药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66712, encryptionId=bf0a66e12f4, topicName=潜在药物)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLc3PoqaNe4QTZ947pojXuchvvmkkJN0wyBBbA3LVX2WDkgiaJ7cswu9yvA4CB0NicjcrCfBY1zRPkA/132, createdBy=b3812500089, createdName=ms6897892027066920, createdTime=Tue Oct 16 05:59:00 CST 2012, time=2012-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1636463, encodeId=01fc1636463d4, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sat Jun 02 20:59:00 CST 2012, time=2012-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759104, encodeId=1ffb1e591045d, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Fri Aug 24 20:59:00 CST 2012, time=2012-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3751, encodeId=22d53e512b, content=糖尿病作为一种代谢性综合征，中药治疗有很大的潜力, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c3e50891, createdName=yiluqianxing, createdTime=Sat Nov 26 01:35:00 CST 2011, time=2011-11-26, status=1, ipAttribution=)]
    2012-10-05 木头人513

    #Diabetes#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1900917, encodeId=9ee0190091e93, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Fri Oct 05 07:59:00 CST 2012, time=2012-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1923680, encodeId=91211923680bb, content=<a href='/topic/show?id=bf0a66e12f4' target=_blank style='color:#2F92EE;'>#潜在药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66712, encryptionId=bf0a66e12f4, topicName=潜在药物)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLc3PoqaNe4QTZ947pojXuchvvmkkJN0wyBBbA3LVX2WDkgiaJ7cswu9yvA4CB0NicjcrCfBY1zRPkA/132, createdBy=b3812500089, createdName=ms6897892027066920, createdTime=Tue Oct 16 05:59:00 CST 2012, time=2012-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1636463, encodeId=01fc1636463d4, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sat Jun 02 20:59:00 CST 2012, time=2012-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759104, encodeId=1ffb1e591045d, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Fri Aug 24 20:59:00 CST 2012, time=2012-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3751, encodeId=22d53e512b, content=糖尿病作为一种代谢性综合征，中药治疗有很大的潜力, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c3e50891, createdName=yiluqianxing, createdTime=Sat Nov 26 01:35:00 CST 2011, time=2011-11-26, status=1, ipAttribution=)]
    2012-10-16 ms6897892027066920

    #潜在药物#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1900917, encodeId=9ee0190091e93, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Fri Oct 05 07:59:00 CST 2012, time=2012-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1923680, encodeId=91211923680bb, content=<a href='/topic/show?id=bf0a66e12f4' target=_blank style='color:#2F92EE;'>#潜在药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66712, encryptionId=bf0a66e12f4, topicName=潜在药物)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLc3PoqaNe4QTZ947pojXuchvvmkkJN0wyBBbA3LVX2WDkgiaJ7cswu9yvA4CB0NicjcrCfBY1zRPkA/132, createdBy=b3812500089, createdName=ms6897892027066920, createdTime=Tue Oct 16 05:59:00 CST 2012, time=2012-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1636463, encodeId=01fc1636463d4, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sat Jun 02 20:59:00 CST 2012, time=2012-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759104, encodeId=1ffb1e591045d, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Fri Aug 24 20:59:00 CST 2012, time=2012-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3751, encodeId=22d53e512b, content=糖尿病作为一种代谢性综合征，中药治疗有很大的潜力, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c3e50891, createdName=yiluqianxing, createdTime=Sat Nov 26 01:35:00 CST 2011, time=2011-11-26, status=1, ipAttribution=)]
    2012-06-02 ms9608593228839890

    #DIA#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1900917, encodeId=9ee0190091e93, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Fri Oct 05 07:59:00 CST 2012, time=2012-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1923680, encodeId=91211923680bb, content=<a href='/topic/show?id=bf0a66e12f4' target=_blank style='color:#2F92EE;'>#潜在药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66712, encryptionId=bf0a66e12f4, topicName=潜在药物)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLc3PoqaNe4QTZ947pojXuchvvmkkJN0wyBBbA3LVX2WDkgiaJ7cswu9yvA4CB0NicjcrCfBY1zRPkA/132, createdBy=b3812500089, createdName=ms6897892027066920, createdTime=Tue Oct 16 05:59:00 CST 2012, time=2012-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1636463, encodeId=01fc1636463d4, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sat Jun 02 20:59:00 CST 2012, time=2012-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759104, encodeId=1ffb1e591045d, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Fri Aug 24 20:59:00 CST 2012, time=2012-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3751, encodeId=22d53e512b, content=糖尿病作为一种代谢性综合征，中药治疗有很大的潜力, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c3e50891, createdName=yiluqianxing, createdTime=Sat Nov 26 01:35:00 CST 2011, time=2011-11-26, status=1, ipAttribution=)]
    2012-08-24 智慧医人

    #BET#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1900917, encodeId=9ee0190091e93, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Fri Oct 05 07:59:00 CST 2012, time=2012-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1923680, encodeId=91211923680bb, content=<a href='/topic/show?id=bf0a66e12f4' target=_blank style='color:#2F92EE;'>#潜在药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66712, encryptionId=bf0a66e12f4, topicName=潜在药物)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLc3PoqaNe4QTZ947pojXuchvvmkkJN0wyBBbA3LVX2WDkgiaJ7cswu9yvA4CB0NicjcrCfBY1zRPkA/132, createdBy=b3812500089, createdName=ms6897892027066920, createdTime=Tue Oct 16 05:59:00 CST 2012, time=2012-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1636463, encodeId=01fc1636463d4, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sat Jun 02 20:59:00 CST 2012, time=2012-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759104, encodeId=1ffb1e591045d, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Fri Aug 24 20:59:00 CST 2012, time=2012-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3751, encodeId=22d53e512b, content=糖尿病作为一种代谢性综合征，中药治疗有很大的潜力, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c3e50891, createdName=yiluqianxing, createdTime=Sat Nov 26 01:35:00 CST 2011, time=2011-11-26, status=1, ipAttribution=)]
    2011-11-26 yiluqianxing

    糖尿病作为一种代谢性综合征，中药治疗有很大的潜力

    0