JACC：局限性内膜撕裂的临床特征研究

2018-06-19 MedSci MedSci原创

主动脉局限性内膜撕裂（LITs）是急性主动脉综合征（AAS）患者的常见形式，但LITs很难通过影像学手段提前检测。本研究的目的旨在比较和评估LITs与其他AAS在发病率、病理学特征、治疗和预后方面的差异。本研究纳入了2003年至2012年诊断的497名AAS患者，并将其分成经典解剖类型（AD）、壁内血肿、LITs、穿透性动脉粥样硬化溃疡和破裂胸主动脉瘤。分析结果发现，共有24例LITs患者（男性占

主动脉局限性内膜撕裂（LITs）是急性主动脉综合征（AAS）患者的常见形式，但LITs很难通过影像学手段提前检测。本研究的目的旨在比较和评估LITs与其他AAS在发病率、病理学特征、治疗和预后方面的差异。

本研究纳入了2003年至2012年诊断的497名AAS患者，并将其分成经典解剖类型（AD）、壁内血肿、LITs、穿透性动脉粥样硬化溃疡和破裂胸主动脉瘤。分析结果发现，共有24例LITs患者（男性占16名，17名A型，7名B型），且患者年龄普遍大于AD患者，A型LITs患者的升主动脉扩张程度与AD患者相似。3名患者发生破裂，11名患者接受了急诊主动脉置换术，2名患者接受了血管内皮修复术。LITs患者的院内死亡率为4%（1/24），共有5名患者在出院后1.5年内相继死亡。另外，对所有LITs患者均进行了计算机断层成像检测，但仅1例LITs患者没有检测到最佳可视化的体积渲染图像。

本研究结果显示，局限性内膜撕裂是急性主动脉综合征中较为罕见的类型，且临床特征和预后与经典解剖类型的AAS相似，通过高质量计算机断层成像检测可以对LITs进行早期诊断。

原始出处：

Anne S et al.Acute Limited Intimal Tears of the Thoracic Aorta.JACC.2018 Jun.

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2018-06-23 hbwxf

#JACC#

24 0
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2019-03-13 yeye5224612

#临床特征#

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2019-02-07 12498974m61暂无昵称

#内膜#

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2018-11-10 haouestc

#局限性#

24 0
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2018-06-21 12498568m50暂无昵称

#ACC#

21 0
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2018-06-20 飛歌

学习了很有用不错

42 0
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2018-06-19 天地飞扬

了解一下.谢谢分享!

50 0
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2018-06-19 医者仁心5538

对临床很有帮助.

45 0

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