BMJ Open:术前肺动脉压可预测风心病换瓣后短期死亡

2017-06-27 许菁 中国循环杂志

置换术后短期死亡。术前肺动脉压> 52.5 mmHg可作为风险评估的切点值。

东省人民医院谭宁等发表研究指出,肺动脉压可预测中老年风湿性二尖瓣病变患者在接受二尖瓣置换术后短期死亡。术前肺动脉压> 52.5 mmHg可作为风险评估的切点值。

本研究中,3.8%中老年风湿性二尖瓣病变患者在二尖瓣置换术后发生院内死亡。

研究纳入1639例患者,院内死亡率伴随肺动脉压的升高而升高,术前肺动脉压≤30 mmHg、30~50 mmHg、50~70 mmHg和>70 mmHg的患者的院内死亡率分别为1.9%、2.3%、4.7%和10.2%。

进一步分析显示,术前肺动脉压>70?mmHg者的院内死亡风险增加近两倍。

术前肺动脉压> 52.5 mmHg预测院内死亡的灵敏度为 60.3%, 特异性67.7%。

术前肺动脉压> 52.5 mmHg患者的术后1年死亡率显着高于肺动脉压正常患者。

研究者发现,术前肺动脉压水平越高,右心室内径越大,心功能越差,严重肺动脉高压阶段已经发生的右心室结构的改变。

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    2018-02-12 feather89
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    2018-04-20 gaoxiaoe
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