Ophthalmologica:玻璃体腔内注射曲安奈德与白内障手术联合治疗效果评估

2018-04-16 cuiguizhong MedSci原创

日本东京女子医科大学东京医学中心眼科的Nunome T近日在Ophthalmologica发表了一篇文章,他们在抗血管内皮生长因子(抗VEGF)治疗的糖尿病性黄斑水肿(DME)患者中,评估玻璃体内注射曲安奈德注射液(IVTA)联合白内障手术治疗方法的有效性。

日本东京女子医科大学东京医学中心眼科的Nunome T近日在Ophthalmologica发表了一篇文章,他们在抗血管内皮生长因子(抗VEGF)治疗的糖尿病性黄斑水肿(DME)患者中,评估玻璃体内注射曲安奈德注射液(IVTA)联合白内障手术治疗方法的有效性。

研究群体为患有屈光抗VEGF治疗的DME患者(年龄70.5±6.2岁),对其29只眼进行IVTA注射并联合白内障手术治疗。在治疗后1、4、12和24周评估视力、中心视网膜厚度(CRT)和视网膜中央敏感性。

结果发现,在治疗后24周,视力从0.49±0.30logMAR单位显着改善至0.35±0.33logMAR单位(p <0.05;重复ANOVA)。治疗后12周,CRT从435.1±112.3μm显着下降至350.8±123.3μm(p <0.05)。治疗后4周,视网膜敏感度阈值从18.2±4.3 dB显着改善至20.4±3.8 dB(p <0.05)。

因此,他们认为,IVTA联合白内障手术对患有抗VEGF治疗的DME屈光度的眼睛是有效的治疗方案。

原文出处:

Nunome, T., et al., Short-Term Results of Intravitreal Triamcinolone Acetonide Combined with Cataract Surgery for Diabetic Macular Edema in Japan: In the Era of Anti-Vascular Endothelial Growth Factor Therapy. Ophthalmologica, 2018.

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    2018-05-17 gujh
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  5. 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  6. 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target=_blank style='color:#2F92EE;'>#THA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17373, encryptionId=5c961e37307, topicName=THA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=615b13300589, createdName=1249842em13(暂无昵称), createdTime=Wed Apr 18 14:36:00 CST 2018, time=2018-04-18, status=1, ipAttribution=)]
    2018-04-19 lofter

    学习了感谢分享

    0

  7. 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  8. 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