治疗神经性疼痛:普瑞巴林是良药

2016-09-25 佚名 Medicalxpress

根据在线发表于9月9日的《疼痛实践》上的研究结果,不管之前有没有用过加巴喷丁,普瑞巴林对于神经性疼痛的治疗都是有益的。 来自纽约罗彻斯特大学医学院的John D. Markman博士和同事们收集了来自在神经性疼痛患者身上进行的18项有关普瑞巴林的随机、双盲试验。作者们比较了普瑞巴林介导的疼痛改变和疼痛相关的睡眠干预得分、最终患者整体印象变化分数以及不良反应在那些之前接受和未接受加巴喷丁的

根据在线发表于9月9日的《疼痛实践》上的研究结果,不管之前有没有用过加巴喷丁,普瑞巴林对于神经性疼痛的治疗都是有益的。

 

来自纽约罗彻斯特大学医学院的John D. Markman博士和同事们收集了来自在神经性疼痛患者身上进行的18项有关普瑞巴林的随机、双盲试验。作者们比较了普瑞巴林介导的疼痛改变和疼痛相关的睡眠干预得分、最终患者整体印象变化分数以及不良反应在那些之前接受和未接受加巴喷丁的患者身上的发生情况。

 

研究人员发现,不管在任何时间点使用多大剂量的普瑞巴林,在之前接受和未接受过加巴喷丁的患者群体之间,疼痛缓解以及疼痛相关睡眠干扰的缓解程度并没有差别。并且,在研究结束时,患者整体印象变化分数或者不良反应的发生情况分布在接受和未接受加巴喷丁治疗的患者群中也没有显著性差异。

 

“这些研究发现支持了一个观点,即普瑞巴林也许能成功用于那些患有神经性疼痛同时对加巴喷丁反应较差或不能耐受的患者。”作者们写道。“这些结果强调了根据个体对不同治疗(包括同种机制下的多种试剂的应用)的反应来调整神经性疼痛治疗的重要性。”

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    2016-10-02 右脚梅西

    很好,有帮助,很喜欢。

    0

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