Diabetic Med:男性2型糖尿病患者肾功能下降风险更大

2014-05-06 伊文 中华医学会糖尿病学分会

近期公布的法国SURDIAGENE研究表明,在2型糖尿病患者中,男性是肾功能下降的重要独立危险因素之一。该研究入选1470例2型糖尿病患者,中位随访5.7年。结果显示,女性和男性患者的平均估算肾小球滤过率每年分别下降1.31 ml/min/1.73 m2和1.77 ml/min/1.73 m2。男性进展为终末期肾脏病的可能性大于女性。校正年龄、确诊糖尿病的事件、糖化血红蛋白水平、收缩压和尿白蛋白肌

近期公布的法国SURDIAGENE研究表明,在2型糖尿病患者中,男性是肾功能下降的重要独立危险因素之一。

该研究入选1470例2型糖尿病患者,中位随访5.7年。结果显示,女性和男性患者的平均估算肾小球滤过率每年分别下降1.31 ml/min/1.73 m2和1.77 ml/min/1.73 m2。男性进展为终末期肾脏病的可能性大于女性。校正年龄、确诊糖尿病的事件、糖化血红蛋白水平、收缩压和尿白蛋白肌酐比值后,男性是估算肾小球滤过率下降的独立危险因素(RR1.33)。多元线性混合效应模型分析进一步证实了这一结果。

原始出处:


de Hauteclocque A1, Ragot S, Slaoui Y, Gand E, Miot A, Sosner P, Halimi JM, Zaoui P, Rigalleau V, Roussel R, Saulnier PJ, Hadjadj Samy S; The SURDIAGENE Study group.The influence of sex on renal function decline in people with Type 2 diabetes.Diabet Med. 2014 Apr 29. doi: 10.1111/dme.12478. [Epub ahead of print]


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    2014-05-09 yese
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    2014-09-05 智智灵药
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