Stroke:每日总体力活动和卒中发生有何关系?

2017-06-06 xing.T MedSci原创

由此可见,适度的体力活动,中等强度的活动,可能是预防卒中的最佳水平,因为过度剧烈活动可能不会产生益处,或对出血性脑卒中的预防不利。

在亚洲人群中,总的体力活动与卒中之间的相关性的证据较为有限,其比西方人群具有更大出血性卒中的负担。近日,卒中领域权威杂志Stroke上发表了一篇研究文章,研究人员旨在明确卒中预防的最佳体力活动水平。

该研究共纳入了74913名50-79岁的没有心血管疾病或癌症病史参与者,并且从2000年随访至2012年。

在698946人次每年的随访中,研究人员共记录到了2738例卒中患者,包括1007例出血性卒中患者(747例脑实质内出血和260例脑蛛网膜下腔出血)和1721例缺血性卒中患者(1206例非栓塞性梗死和515例栓塞性梗死)。研究人员发现每天任务小时代谢当量在第二或第三个四分位数范围的参与者总的卒中(风险比[HR]为0.83;95%可信区间[CI]为0.75-0.93)、脑出血(HR为0.79;95%CI为0.64-0.97)、蛛网膜下腔出血(HR为0.78;95%CI为0.55-1.11)和非栓塞性梗死(HR为0.78;95%CI为0.67-0.92)风险最低,而在第四个四分位数范围的参与者栓塞性脑梗死的风险最低(HR为0.76;95%CI为0.59-0.97)。三次样条曲线显示卒中风险从最低水平急剧下降(风险降低30%)至5至10个每天任务小时的代谢当量(第五十百分位数)的平台期。总的体力活动水平与出血性脑卒中之间的关系表现为U或J型,这是由于较为剧烈的体力活动,而与缺血性卒中之间的关系呈L形。

由此可见,适度的体力活动,中等强度的活动,可能是预防卒中的最佳水平,因为过度剧烈活动可能不会产生益处,或对出血性脑卒中的预防不利。

原始出处:

Yasuhiko Kubota, et al. Daily Total Physical Activity and Incident Stroke The Japan Public Health Center–Based Prospective Study.Stroke. 2017. https://doi.org/10.1161/STROKEAHA.117.017560

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  1. [GetPortalCommentsPageByObjectIdResponse(id=207695, encodeId=b23b20e69576, content=生命在于运动, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220317/1c3b2db4747d42e88e5018b394979434/be0fcebf07344e9ab886c37c502e2f29.jpg, createdBy=6bb22051299, createdName=微笑人参, createdTime=Wed Jun 07 11:57:19 CST 2017, time=2017-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=207602, encodeId=ee1f20e602d9, content=学习了,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Wed Jun 07 08:21:10 CST 2017, time=2017-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=207534, encodeId=64ad20e53415, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Wed Jun 07 06:50:35 CST 2017, time=2017-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=207462, encodeId=368f20e46226, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuCl4zaE0zq0kFsKQmg3vef7gFticiaFX50TWZibZibNHbk3YSJ5uSh1a0DcUiaVIHkoe2Om3eYg7oUTlf/0, createdBy=442c2063958, createdName=海棠胜雪, createdTime=Wed Jun 07 00:03:29 CST 2017, time=2017-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=207452, encodeId=1f0420e4525f, content=合乎情理的科学证据, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCclExeQ6LOGMD4dTsia4Ty4HtZCxRmG5vO5XIKfKX3a3vusfhHSej4Iib517vmhFW7RQgh7bpDp1yw/0, createdBy=50951609779, createdName=baihao215, createdTime=Tue Jun 06 23:40:10 CST 2017, time=2017-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=207327, encodeId=400920e32771, content=学习啦谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Tue Jun 06 13:02:10 CST 2017, time=2017-06-06, status=1, ipAttribution=)]
    2017-06-07 微笑人参

    生命在于运动

    0

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    2017-06-07 qingfengqishi5

    学习了,学习了

    0

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    2017-06-07 meiliwuxian

    学习了

    0

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    2017-06-07 海棠胜雪

    学习了

    0

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    2017-06-06 baihao215

    合乎情理的科学证据

    0

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    2017-06-06 tanxingdoctor

    学习啦谢谢分享

    0

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