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Circulation：外科主动脉瓣置换术后临床卒中常见

2014-04-04 高晓方 译 医学论坛网

主动脉瓣置换术AVR卒中
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美国一项研究表明，外科主动脉瓣置换(AVR)术后临床卒中发生率高于既往胸外科学会(STS)所报告的，并且超过半数患者可在AVR后检出隐匿性脑梗死;AVR术后卒中的并发症与住院时间和死亡率增加有相关性。论文于4月1日在线发表于《循环》(Circulation)。 此项研究共纳入196例因钙化性主动脉狭窄而接受AVR治疗的患者。神经科医生在术前和术后对受试者进行评估，并在术后实施MRI检查。受试者平

美国一项研究表明，外科主动脉瓣置换(AVR)术后临床卒中发生率高于既往胸外科学会(STS)所报告的，并且超过半数患者可在AVR后检出隐匿性脑梗死;AVR术后卒中的并发症与住院时间和死亡率增加有相关性。论文于4月1日在线发表于《循环》(Circulation)。

此项研究共纳入196例因钙化性主动脉狭窄而接受AVR治疗的患者。神经科医生在术前和术后对受试者进行评估，并在术后实施MRI检查。受试者平均年龄为75.8 ± 6.2岁，女性占36%，非白人受试者占6%。

结果显示，临床卒中、短暂性脑缺血发作和院内死亡的发生率分别为17%、2%和5%。在STS数据库中，该人群的卒中发生率为7%。大部分卒中为轻度，中位NIHSS为3。临床卒中与住院时间延长具有相关性，中、重度卒中则与院内死亡显著相关。在术后接受MRI检查的109例无卒中受试者中，59例(54%)检出隐匿性梗死。隐匿性梗塞与院内死亡或住院时间延长均无相关性。

原始出处：


Messé SR1, Acker MA, Kasner SE, Fanning M, Giovannetti T, Ratcliffe SJ, Bilello M, Szeto WY, Bavaria JE, Hargrove WC 3rd, Mohler ER 3rd, Floyd TF; for the Determining Neurologic Outcomes from Valve Operations (DeNOVO) investigators.Stroke after Aortic Valve Surgery: Results from a Prospective Cohort.Circulation. 2014 Apr 1. 

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    2014-11-12 xiaoshitou

    #外科主动脉瓣置换术#

    0

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    2014-11-21 yxch48

    #置换#

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    2014-04-06 hittouch

    #主动脉瓣#

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    2014-04-06 medsci246

    #主动脉瓣置换术#

    0

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    2014-04-06 circumcision

    #主动脉#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1952545, encodeId=ffcb195254501, content=<a href='/topic/show?id=3d594291393' target=_blank style='color:#2F92EE;'>#外科主动脉瓣置换术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42913, encryptionId=3d594291393, topicName=外科主动脉瓣置换术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0357291, createdName=xiaoshitou, createdTime=Wed Nov 12 06:48:00 CST 2014, time=2014-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1742277, encodeId=8be11e4227742, content=<a href='/topic/show?id=39cae96626f' target=_blank style='color:#2F92EE;'>#置换#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79662, encryptionId=39cae96626f, topicName=置换)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3a7c35056336, createdName=yxch48, createdTime=Fri Nov 21 13:48:00 CST 2014, time=2014-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1332355, encodeId=794b1332355c0, content=<a href='/topic/show?id=1dd6231822d' target=_blank style='color:#2F92EE;'>#主动脉瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23182, encryptionId=1dd6231822d, topicName=主动脉瓣)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc4b2500077, createdName=hittouch, createdTime=Sun Apr 06 07:48:00 CST 2014, time=2014-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367065, encodeId=8859136e06536, content=<a href='/topic/show?id=b6222320322' target=_blank style='color:#2F92EE;'>#主动脉瓣置换术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23203, encryptionId=b6222320322, topicName=主动脉瓣置换术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b24249, createdName=medsci246, createdTime=Sun Apr 06 07:48:00 CST 2014, time=2014-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1414971, encodeId=655c14149e13c, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Sun Apr 06 07:48:00 CST 2014, time=2014-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576479, encodeId=86ab15e647997, content=<a href='/topic/show?id=48fee966468' target=_blank style='color:#2F92EE;'>#置换术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79664, encryptionId=48fee966468, topicName=置换术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=054816326830, createdName=ms117281293605716, createdTime=Sun Apr 06 07:48:00 CST 2014, time=2014-04-06, status=1, ipAttribution=)]
    2014-04-06 ms117281293605716

    #置换术#

    0