Radiology:内囊梗死和脑桥梗死的结构改变和结构功能性代偿的不同模式

2017-08-14 shaosai MedSci原创

内囊是大脑皮层与脑干、脊髓联系的神经纤维通过的一个部位的名称,位于基底神经节与丘脑之间。通往大脑皮层的运动神经纤维和感觉神经纤维,均经内囊向上呈扇形放射状分布。肌紧张和肌肉运动是由脑干网状结构控制的。脑桥网状核是网状结构易化区域之一。脑桥的被盖和延髓网状结构背外侧部、中脑中央灰质以及下丘脑后部和丘脑中缝核群等共同对同侧伸肌起调节作用,主要是易化性影响。另外,在大脑-脑桥-小脑之间形成一个环形联系,

内囊是大脑皮层与脑干、脊髓联系的神经纤维通过的一个部位的名称,位于基底神经节与丘脑之间。通往大脑皮层的运动神经纤维和感觉神经纤维,均经内囊向上呈扇形放射状分布。肌紧张和肌肉运动是由脑干网状结构控制的。脑桥网状核是网状结构易化区域之一。脑桥的被盖和延髓网状结构背外侧部、中脑中央灰质以及下丘脑后部和丘脑中缝核群等共同对同侧伸肌起调节作用,主要是易化性影响。另外,在大脑-脑桥-小脑之间形成一个环形联系,共同协调肌肉运动。本研究为了探究内囊卒中与脑桥卒中累及运动传导束的患者是否会发生不同的结构破坏及重组,并将结果发表在Radiology上。

本研究前瞻性分析了来自三家医院的115例CS、47例PS和116名健康志愿者的MRI图像。分析患者病变位置(随访检查时间:平均为597天,范围180-2070天)。待定年龄、性别和扫描者的影响,将每个体素的灰质体积(GMV)进行两两比较。多重比较通过错误发现率的方法对每个体素进行比较,并利用Bonferroni法进行事后比较。

在CS组和PS组病人都出现了病变同侧前岛叶皮层GMV的减少(6.18%-8.23%),与对照组相比在代偿运动区域GMV增加(5.11%-11.73%) (P < .0013)。另外,在所有CS组患者(9.73%-10.41%)病变同侧运动感觉皮层和所有PS组患者(10.58%-15.81%)小脑出现了GMV减少。在PS组左侧病变(17.23%)患者的楔前叶和CS组右侧病变(10.95%)的额中回出现GMV增加。

本研究表明,CS和PS患者出现不同模式的结构破坏和结构功能性重组,这也有助于个体化康复治疗策略的制定。

原始出处:

Jiang L, Liu J, Wang C , et al,Structural Alterations in Chronic Capsular versus Pontine Stroke.  Radiology. 2017.DOI: 10.1148/radiol.2017161055

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    2018-05-01 amy0560
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    2017-08-15 海之蓝

    谢谢

    0

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    2017-08-15 meiliwuxian

    学习了

    0

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    2017-08-15 baihao215

    厉害了,涨姿势

    0

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    2017-08-14 QQ25ed180f

    进一步学习了~

    0

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    2017-08-14 天涯183

    非常好的文章,学习了,很受益

    0

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    2017-08-14 忠诚向上

    好好学习努力

    0

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    2017-08-14 1771ae4158m

    学习一下很不错

    0

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