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Heart：家庭空气污染与血压、动脉僵硬度和中央血液动力学相关性分析！

2018-02-10 xing.T MedSci原创

家庭空气污染血压动脉僵硬度中央血液动力学相关性
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由此可见，暴露于家庭空气污染与中国老年妇女血压升高和中央血流动力学有关，而与脉搏波速度没有观察到相关性。

近日，在心脏病领域权威杂志Heart上发表了一篇研究文章，研究人员旨在评估中国农村女性生物燃料炉灶的空气污染暴露与多种血管和血液动力学参数之间的暴露-反应之间的相关性。

研究人员分析了中国西南地区纵向研究的基线信息。测量了夏季和冬季的女性肱动脉和中心血压和脉压、颈-股脉搏波速度和增强指数以及个人48小时细颗粒物（PM2.5）和黑碳接触情况。研究人员使用针对已知心血管危险因素进行调整的混合效应回归模型评估空气污染暴露和血液动力学参数之间的相关性。

女性（n=205，年龄27-86岁）暴露于PM2.5和黑碳的剂量范围分别为14μg/m3到1405μg/m3和0.1-121.8μg/m3。在≥50岁的女性中，PM2.5暴露增加与较高的收缩压（肱动脉：3.5mmHg（P=0.05），中央动脉：4.4mmHg（P=0.005））和舒张压（中央动脉：1.3mmHg（P=0.10））、更高的脉压（肱动脉：2.5mmHg（P=0.05）;中央动脉：4.7mmHg（P=0.008））和较低的外周中央脉压扩增（-0.007（P=0.04））相关。在年轻女性中，这些相关性在效果方面并不一致，而且没有统计学意义。虽然可信区间包含零（1.1％; 95％可信区间为-0.2％至2.4％），但是PM2.5暴露增加与脉搏波速度没有差异且增强指数略高有关。与黑碳暴露也可以观察到类似的相关性。

由此可见，暴露于家庭空气污染与中国老年妇女血压升高和中央血流动力学有关，而与脉搏波速度没有观察到相关性。

原始出处：

Jill Baumgartner,et al. Household air pollution and measures of blood pressure, arterial stiffness and central haemodynamics. Heart. 2018. http://dx.doi.org/10.1136/heartjnl-2017-312595

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    2018-07-15 doctorzheng

    #中央血液动力学#

    0

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    2018-06-15 shenxlcyp

    #相关性#

    0

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    2018-08-31 huirong

    #血液动力学#

    0

  4. 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    2018-02-12 wmw990556

    学习中..

    0

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    2018-02-12 zhaojie88

    #ART#

    0

  6. 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createdName=1696533704_45270458, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562824, encodeId=0581156282481, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=)]
    2018-02-12 小刀医生

    #污染#

    0

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encodeId=ae5a1546e42a2, content=<a href='/topic/show?id=de1233215db' target=_blank style='color:#2F92EE;'>#动脉僵硬#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33215, encryptionId=de1233215db, topicName=动脉僵硬)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b48f13938152, createdName=dlwang_26703131, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546804, encodeId=f93d1546804cf, content=<a href='/topic/show?id=96a0332168b' target=_blank style='color:#2F92EE;'>#动脉僵硬度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33216, encryptionId=96a0332168b, topicName=动脉僵硬度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eb8013942519, createdName=1696533704_45270458, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562824, encodeId=0581156282481, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=)]
    2018-02-12 anminleiryan

    #相关性分析#

    0

  8. 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objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64361, encryptionId=ba4a6436107, topicName=污染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dfe67217539, createdName=小刀医生, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523598, encodeId=7365152359853, content=<a href='/topic/show?id=f6f1e2533e3' target=_blank style='color:#2F92EE;'>#相关性分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72533, encryptionId=f6f1e2533e3, topicName=相关性分析)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad8f11536374, createdName=anminleiryan, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546742, encodeId=ae5a1546e42a2, content=<a href='/topic/show?id=de1233215db' target=_blank style='color:#2F92EE;'>#动脉僵硬#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33215, encryptionId=de1233215db, topicName=动脉僵硬)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b48f13938152, createdName=dlwang_26703131, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546804, encodeId=f93d1546804cf, content=<a href='/topic/show?id=96a0332168b' target=_blank style='color:#2F92EE;'>#动脉僵硬度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33216, encryptionId=96a0332168b, topicName=动脉僵硬度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eb8013942519, createdName=1696533704_45270458, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562824, encodeId=0581156282481, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=)]
    2018-02-12 dlwang_26703131

    #动脉僵硬#

    0

  9. 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objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64361, encryptionId=ba4a6436107, topicName=污染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dfe67217539, createdName=小刀医生, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523598, encodeId=7365152359853, content=<a href='/topic/show?id=f6f1e2533e3' target=_blank style='color:#2F92EE;'>#相关性分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72533, encryptionId=f6f1e2533e3, topicName=相关性分析)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad8f11536374, createdName=anminleiryan, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546742, 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createdName=1696533704_45270458, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562824, encodeId=0581156282481, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=)]
    2018-02-12 1696533704_45270458

    #动脉僵硬度#

    0

  10. 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encodeId=ae5a1546e42a2, content=<a href='/topic/show?id=de1233215db' target=_blank style='color:#2F92EE;'>#动脉僵硬#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33215, encryptionId=de1233215db, topicName=动脉僵硬)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b48f13938152, createdName=dlwang_26703131, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546804, encodeId=f93d1546804cf, content=<a href='/topic/show?id=96a0332168b' target=_blank style='color:#2F92EE;'>#动脉僵硬度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33216, encryptionId=96a0332168b, topicName=动脉僵硬度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=eb8013942519, createdName=1696533704_45270458, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562824, encodeId=0581156282481, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Mon Feb 12 05:33:00 CST 2018, time=2018-02-12, status=1, ipAttribution=)]
    2018-02-12 slcumt

    #HEART#

    0

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