NEJM:I型和II型糖尿病患者的死亡率和心血管疾病事件发生率 1998-2014

2017-04-13 MedSci MedSci原创

瑞典1998至2014年间,糖尿病患者的死亡率和心血管事件发生率大幅下降且II型糖尿病患者死亡率下降

I型或II型糖尿病患者的死亡和心血管事件率的长期变化趋势尚未系统研究,近日瑞典科学家在新一期的新英格兰医学杂志公布最新的研究成果。

研究人员统计了1998年至2014年间,瑞典国家糖尿病协会登记的糖尿病患者死亡以及心血管事件的发生率,用Cox回归和标准化发病率估计死亡和心血管事件的趋势。

结果显示,I型糖尿病患者中,研究期间每10000人数年发病率绝对变化如下:任何原因的死亡,减少31.4(95% CI -56.1至-6.7);冠心病死亡减少21.7(95% CI -37.1至-6.4);心血管疾病住院减少45.7(95% CI -71.4至-20.1)。II型糖尿病患者中,研究期间每10000人数年发病率绝对变化如下:任何原因的死亡,减少69.6(95% CI -95.9至-43.2);心血管疾病死亡减少110.0(95% CI -128.9至-91.1);冠心病死亡减少91.9(95% CI -108.9至-75);心血管疾病住院减少203.6(95% CI -230.9至-176.3)。I型糖尿病患者的心血管事件减少约40%,II型糖尿病患者的心血管事件减少约20%;I型糖尿病患者与对照组的死亡率相似,II型糖尿病患者的死亡率较对照下降。

瑞典1998至2014年间,糖尿病患者的死亡率和心血管事件发生率大幅下降且II型糖尿病患者死亡率下降。

原文出处:

Aidin Rawshani et al. Mortality and Cardiovascular Disease in Type 1 and Type 2 Diabete. N Engl J Med. 2017-4-13.

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