癌症免疫疗法先驱Allison获得2014年圣.乔奇癌症研究创新成就奖

2014-02-09 佚名 生物探索

日前,美国国家癌症研究基金会(National Foundation for Cancer Research,NFCR)宣布将第9届圣.乔奇癌症研究创新成就奖(Szent-Györgyi Prize for Progress in Cancer Research)授予德克萨斯大学安德森免疫学学院癌症中心(University of Texas MD Anderson Cancer Center

日前,美国国家癌症研究基金会(National Foundation for Cancer Research,NFCR)宣布将第9届圣.乔奇癌症研究创新成就奖(Szent-Györgyi Prize for Progress in Cancer Research)授予德克萨斯大学安德森免疫学学院癌症中心(University of Texas MD Anderson Cancer Center Department of Immunology)的Jim Allison,以表彰其在癌症免疫疗法上所作出的杰出贡献。

Szent-Gyorgyi奖由NFCR于2006年设立,为了纪念已故的诺贝尔奖得主(1937)以及 NFCR的联合创始人Albert Szent-Györgyi。奖项每年奖励在癌症研究领域获得突破的研究者,该奖项的资助者很有可能是未来攻克癌症的前沿阵地。获奖者将得到2.5万美元的奖励。授奖仪式将在今年4月30日进行。

1980年代末,癌症的免疫疗法初见端倪,法国研究者发现在T细胞上有一种叫做CTLA-4的受体。James Allison发现该受体会阻止T细胞全力攻击入侵者。1990年代中期,Allison证明,在小鼠中阻断CTLA-4可在小鼠中解除T细胞对肿瘤细胞进行攻击的束缚,从而使肿瘤细胞大幅萎缩。新加坡科学技术和研究总署实验治疗中心执行总裁、2013年Szent Gyorgyi获得者 Alax Matter说,“Allison博士的工作挽救了无数人的生命,并为肿瘤学未来发展指明方向。”他也是今年该奖项评选委员会的主席。

“他的免疫疗法已深入人心,并扭转了过去人们对治疗癌症的看法,” Matter在NFCR的一份声明中称,“他的工作极其重要,是癌症治疗领域的一个转折点。”

同样,鼓舞人心的癌症免疫疗法2013年被《科学》杂志评为该年度最重要的科学突破。

尽管,刚刚过去的2月4日“世界癌症日”WHO发布最新的研究报告称,2012年全球有1400万人被诊断患癌,2035年这一数字将增至2400万。但是癌症免疫疗法仍会是治疗癌症的有效手段。

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    2014-02-11 lilianxiang
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    2014-02-11 膀胱癌
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