期刊: BIOCHEMICAL JOURNAL, 2023; 480 (22)
Plants are vital to human health and well-being, as well as helping to protect the environment against the negative impacts of climate change. They ar......
期刊: BIOCHEMICAL JOURNAL, 2023; 480 (19)
The protein kinase PDK1 phosphorylates at least 24 distinct substrates, all of which belong to the AGC protein kinase group. Some substrates, such as ......
期刊: BIOCHEMICAL JOURNAL, 2023; 480 (22)
Enzymes have been shaped by evolution over billions of years to catalyse the chemical reactions that support life on earth. Dispersed in the literatur......
期刊: BIOCHEMICAL JOURNAL, 2023; 480 (11)
Carbon storage in soils is one of the most promising strategies for mitigating greenhouse gas emissions and the associated climate change. In this con......
期刊: BIOCHEMICAL JOURNAL, 2023; 480 (15)
The development and optimisation of a photoaffinity labelling (PAL) displacement assay is presented, where a highly efficient PAL probe was used to re......
期刊: BIOCHEMICAL JOURNAL, 2023; 480 (19)
Inclusion body formation is associated with cytotoxicity in a number of neurodegenerative diseases. However, the molecular basis of the toxicity cause......
期刊: BIOCHEMICAL JOURNAL, 2023; 480 (14)
RhoGAP6 is the most highly expressed GTPase-activating protein (GAP) in platelets specific for RhoA. Structurally RhoGAP6 contains a central catalytic......
期刊: BIOCHEMICAL JOURNAL, 2023; 480 (19)
In this paper, we describe the development of a Dictyostelium discoideum strain deficient in frataxin protein (FXN). We investigated the conservation ......
期刊: BIOCHEMICAL JOURNAL, 2023; 480 (24)
The stringent regulation of RAGs (Recombination activating genes), the site-specific endonuclease responsible for V(D)J recombination, is important to......
期刊: BIOCHEMICAL JOURNAL, 2023; 480 (12)
Plant receptor kinases (RKs) function as key plasma-membrane localized receptors in the perception of molecular ligands regulating development and env......
期刊: BIOCHEMICAL JOURNAL, 2023; 480 (24)
The SLC7A11/xCT cystine and glutamate antiporter has emerged as an attractive target for cancer therapy due to its selective overexpression in multipl......
期刊: BIOCHEMICAL JOURNAL, 2023; 480 (11)
The main protease of SARS-CoV-2, 3-chymotrypsin-like protease (3CLpro), is a prominent target for antiviral development due to its essential role in t......
期刊: BIOCHEMICAL JOURNAL, 2023; 480 (13)
Plants require the major macronutrients, nitrogen (N), phosphorus (P) and potassium (K) for normal growth and development. Their deficiency in soil di......
期刊: BIOCHEMICAL JOURNAL, 2023; 480 (20)
Prostate cancer is one of the most common cancers in men and one of the top causes of death in men worldwide. Development and function of both normal ......
期刊: BIOCHEMICAL JOURNAL, 2023; 480 (9)
Plant growth and development are governed by selective protein synthesis and degrad-ation. Ubiquitination mediated protein degradation is governed by ......