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Role of endoplasmic reticulum stress in apoptosis induced by HK2 inhibitor and its potential as a new drug combination strategy

期刊: CELL STRESS & CHAPERONES, 2022; 27 (3)

Compared with normal cells, tumor cells mainly obtain energy through aerobic glycolysis. Hexokinase 2 (HK2) plays a key role in the regulation of tumo......

JIF:2.954

Effects of Lycium barbarum glycopeptide on renal and testicular injury induced by di(2-ethylhexyl) phthalate

期刊: CELL STRESS & CHAPERONES, 2022; 27 (3)

Di(2-ethylhexyl) phthalate (DEHP) is a common environmental pollutant with renal and reproductive toxicity. Lycium barbarum glycopeptide (LbGp) is the......

JIF:2.954

UFL1 alleviates ER stress and apoptosis stimulated by LPS via blocking the ferroptosis pathway in human granulosa-like cells

期刊: CELL STRESS & CHAPERONES, 2022; 27 (5)

Ubiquitin-like modifier 1 ligating enzyme 1 (UFL1) is a unique E3 ligase of the UFMylation system. Recent studies have shown that this enzyme plays a ......

JIF:2.954

Prophylactic role of olive fruit extract against cigarette smoke-induced oxidative stress in Sprague-Dawley rats

期刊: CELL STRESS & CHAPERONES, 2022; 27 (5)

Cigarette smoke exposure increases the production of free radicals leading to initiation of several pathological conditions by triggering the oxidativ......

JIF:2.954

Sequence similarity of HSP65 of Mycobacterium bovis BCG with SARS-CoV-2 spike and nuclear proteins: may it predict an antigen-dependent immune protection of BCG against COVID-19?

期刊: CELL STRESS & CHAPERONES, 2022; 27 (1)

The Bacillus Calmette-Guerin (BCG) vaccine is known to have protective effects not only against tuberculosis but also against other unrelated infectio......

JIF:2.954

Mechanism of miR-455-3 in suppressing epithelial-mesenchymal transition and angiogenesis of non-small cell lung cancer cells

期刊: CELL STRESS & CHAPERONES, 2022; 27 (2)

The tumor-suppressing role of miR-455-3p has been reported in lung cancer, but the working mechanism remains to be fully elucidated. This study aims t......

JIF:2.954

MicroRNA-214-3p aggravates ferroptosis by targeting GPX4 in cisplatin-induced acute kidney injury

期刊: CELL STRESS & CHAPERONES, 2022; 27 (4)

Acute kidney injury (AKI) induced by cisplatin (cis-AKI) involves indicators such as inflammation and oxidative stress (OS) in proximal tubules, altho......

JIF:2.954

Camel whey protein alleviates heat stress-induced liver injury by activating the Nrf2/HO-1 signaling pathway and inhibiting HMGB1 release

期刊: CELL STRESS & CHAPERONES, 2022; 27 (4)

This study aimed to investigate the mechanism by which camel whey protein (CWP) inhibits the release of high-mobility group box 1 (HMGB1) in heat stre......

JIF:2.954

RNA binding motif protein 3 (RBM3) promotes protein kinase B (AKT) activation to enhance glucose metabolism and reduce apoptosis in skeletal muscle of mice under acute cold exposure

期刊: CELL STRESS & CHAPERONES, 2022; 27 (6)

The main danger of cold stress to animals in cold regions is systemic metabolic changes and protein synthesis inhibition. RBM3, an exceptional cold sh......

JIF:2.954

Cloning and expression studies on glutathione S-transferase like-gene in honey bee for its role in oxidative stress

期刊: CELL STRESS & CHAPERONES, 2022; 27 (2)

Glutathione S-transferases (GSTs) constitute an important multifunctional enzyme family that plays vital roles in cellular detoxification and protecti......

JIF:2.954

Hsp90 and phosphorylation of the Slt2(Mpk1) MAP kinase activation loop are essential for catalytic, but not non-catalytic, Slt2-mediated transcription in yeast

期刊: CELL STRESS & CHAPERONES, 2022; 27 (3)

In yeast, the Slt2(Mpk1) stress-activated protein kinase directs the activation of two transcription factors, Rlm1 and Swi4/Swi6, in response to cell ......

JIF:2.954

ER-stress-induced secretion of circulating glucose-regulated protein 78kDa (GRP78) ameliorates pulmonary artery smooth muscle cell remodelling

期刊: CELL STRESS & CHAPERONES, 2022; 27 (5)

Pulmonary arterial hypertension (PAH) is driven by vascular remodelling due to inflammation and cellular stress, including endoplasmic reticulum stres......

JIF:2.954

Antioxidant defense of fish collagen peptides attenuates oxidative stress in gastric mucosa of experimentally ulcer-induced rats

期刊: CELL STRESS & CHAPERONES, 2022; 27 (1)

The aim of the present study was to investigate the ability of fish collagen peptides (FCP) from the skin of great hammerhead shark (Sphyrna mokarran)......

JIF:2.954

ALDH3B1 protects interfollicular epidermal cells against lipid peroxidation via the NRF2 pathway

期刊: CELL STRESS & CHAPERONES, 2022; 27 (6)

Reactive oxygen species (ROS) production is critical for the initiation of wound repair; however, persistently high levels of ROS can lead to lipid pe......

JIF:2.954

Canine osteosarcoma cells exhibit basal accumulation of multiple chaperone proteins and are sensitive to small molecule inhibitors of GRP78 and heat shock protein function

期刊: CELL STRESS & CHAPERONES, 2022; 27 (3)

Osteosarcoma is the most common type of bone cancer in dogs and humans, with significant numbers of patients experiencing treatment failure and diseas......

JIF:2.954

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