期刊： CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 36 (9)
In silico approaches have acquired atoweringrole in pharmaceutical research and development, allowing laboratoriesall around the world to design, crea......
期刊： CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 36 (7)
Unpredicted human organ level toxicity remains one ofthe majorreasons for drug clinical failure. There is a critical need for cost-efficientstrategies......
期刊： CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 36 (12)
Epigallocatechin-3-O-gallate (EGCG) is the major component of green tea extract, commonly found in dietary supplements, and has been associated with i......
期刊： CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 36 (11)
Chronic exposure to inorganic arsenic (As) [As(III) + As(V)], which affects millions of people, increases the incidence of some kinds of cancer and ot......
期刊： CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 36 (12)
Metabolism helps in the elimination of drugs from the human body by making them more hydrophilic. Sometimes, drugs can be bioactivated to highly react......
期刊： CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 36 (11)
Methylglyoxal (MGO) and glyoxal (GO) are toxic alpha-dicarbonyl compounds that undergo reactions with amine containing molecules such as proteins and ......
期刊： CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 36 (12)
Ischemic stroke is a major cause of death and disability worldwide. However, only intravenous thrombolysis using mechanical thrombectomy or tissue pla......
期刊： CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 36 (6)
Motivations for understanding the underlying mechanismsof alcoholtoxicity range from economical to toxicological and clinical. On theone hand, acute a......
期刊： CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 36 (9)
Sulfur mustard [HD; bis-(2-chloroethyl) sulfide] and other analogues are a kind of highly toxic vesicant and have been prohibited by the Organization ......
期刊： CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 36 (10)
Epidemiological studies aim to assess associations between diseases and risk factors. Such investigations involve a large sample size and require powe......
期刊： CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 37 (1)
The surfactant sodium lauryl sulfate (SLS), although consistently positive in the murine local lymph node assay (LLNA) for skin sensitization, shows n......
期刊： CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 36 (7)
Exposure to environmental tobacco smoke (ETS), whichcontains hundredsof toxic compounds, significantly increases the risk of developingmany human dise......
期刊： CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 36 (7)
Mitochondrial toxicityis a significant concern in the drug discoveryprocess, as compounds that disrupt the function of these organellescan lead to ser......
期刊： CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 36 (4)
The emergence and re-emergence of bacterial strains resistant to multiple drugs represent a global health threat, and the search for novel biological ......
期刊： CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 36 (5)
Our previous studies found that di (2-ethylhexyl) phthalate (DEHP) could disorder lipid metabolism in adolescents but the mechanisms underlying this a......
