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Shenhuang plaster enhances intestinal anastomotic healing in rabbits through activation of the TGF-β and Hippo/YAP signaling pathways

期刊: JOURNAL OF APPLIED BIOMEDICINE, 2023; 21 (4)

Although many efforts have been made to improve management strategies and diagnostic methods in the past several decades, the prevention of anastomoti......

The hepatoprotective effect of Sophora viciifolia fruit extract against acetaminophen-induced liver injury in mice

期刊: JOURNAL OF APPLIED BIOMEDICINE, 2023; 21 (2)

This research demonstrated the protective effect and possible mechanism of the Sophora viciifolia extract (SVE) against acetaminophen-induced liver in......

Resting-state EEG alpha rhythm spectral power in children with specific language impairment: a cross-sectional study

期刊: JOURNAL OF APPLIED BIOMEDICINE, 2023; 21 (3)

Purpose: This study investigated EEG alpha rhythm spectral power in children with Specific Language Impairment (SLI) and compared it to typically deve......

Amaryllidaceae alkaloids in skin cancer management: Photoprotective effect on human keratinocytes and anti-proliferative activity in melanoma cells

期刊: JOURNAL OF APPLIED BIOMEDICINE, 2023; 21 (1)

Skin cancer has high rates of mortality and therapeutic failure. In this study, to develop a multi-agent strategy for skin cancer management, the sele......

Causality assessment of adverse drug reaction: A narrative review to find the most exhaustive and easy-to-use tool in post-authorization settings

期刊: JOURNAL OF APPLIED BIOMEDICINE, 2023; 21 (2)

Background: The core motive of pharmacovigilance is the detection and prevention of adverse drug reactions (ADRs), to improve the risk-benefit balance......

hKLK alleviates myocardial fibrosis in mice with viral myocarditis

期刊: JOURNAL OF APPLIED BIOMEDICINE, 2023; 21 (1)

Myocardial fibrosis is the most serious complication of viral myocarditis (VMC). This study aimed to investigate the therapeutic benefits and underlyi......

Anticancer and antimicrobial evaluation of extract from brown algae Hormophysa cuneiformis

期刊: JOURNAL OF APPLIED BIOMEDICINE, 2023; 21 (3)

Aim: We investigated the antimicrobial and anticancer properties of an ethanol crude extract of Red Sea brown alga (Hormophysa Methods: Extraction was......

Naringin inhibits P2X4 receptor expression on satellite glial cells in the neonatal rat dorsal root ganglion

期刊: JOURNAL OF APPLIED BIOMEDICINE, 2023; 21 (4)

Naringin inhibits inflammation and oxidative stress, the P2 purinoreceptor X4 receptor (P2X4R) is associated with glial cell activation and inflammati......

Allele frequency and genotype distribution of the opioid receptor μ-1 (OPRM1) A118G polymorphism in the Western Saudi population

期刊: JOURNAL OF APPLIED BIOMEDICINE, 2023; 21 (3)

The single nucleotide polymorphism (SNP) A118G (rs1799971) in the Mu Opioid Receptor 1 (OPRM1) gene is associated with significant variations in analg......

Sequential hybrid ablation versus surgical CryoMaze alone for treatment of atrial fibrillation (SurHyb Trial): a protocol of the multicentre randomized controlled trial

期刊: JOURNAL OF APPLIED BIOMEDICINE, 2023; 21 (2)

Background: Atrial fibrillation is common in patients with structural heart disease who are undergoing cardiac surgery. Surgical CryoMaze has been sho......

As a novel anticancer candidate, ether extract of Dendrobium nobile overstimulates cellular protein biosynthesis to induce cell stress and autophagy

期刊: JOURNAL OF APPLIED BIOMEDICINE, 2023; 21 (1)

Increasing data has confirmed the potential anticancer properties of Dendrobium, a traditional Chinese herb. However, most anticancer compositions fro......

Ginsenoside Rb2 improves heart failure by down-regulating miR-216a-5p to promote autophagy and inhibit apoptosis and oxidative stress

期刊: JOURNAL OF APPLIED BIOMEDICINE, 2023; 21 (4)

Background: Ginsenoside Rb2 is beneficial in cardiovascular disease treatment, yet its role in heart failure (HF) is obscure. This study aimed to inve......

Closed reduction and minimally invasive screw osteosynthesis of Pipkin femoral head fractures

期刊: JOURNAL OF APPLIED BIOMEDICINE, 2023; 21 (1)

Background: Femoral posterior hip dislocation with associated femoral head fractures (Pipkin fractures) are rare high-energy injuries. Published treat......

Comparison of cardiocerebrovascular disease incidence between angiotensin converting enzyme inhibitor and angiotensin receptor blocker users in a real-world cohort

期刊: JOURNAL OF APPLIED BIOMEDICINE, 2023; 21 (1)

Background: Both angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) are known to be effective in managing ca......

In vitro study of Nigella sativa and thymoquinone activity on endothelial activation and monocyte adhesion

期刊: JOURNAL OF APPLIED BIOMEDICINE, 2023; 21 (2)

Introduction: Thymoquinone (TQ) is one of the bioactive compounds in Nigella sativa (NS). Also known as black seeds/cumin, it has been postulated to p......

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