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Electrochemical sensor based on molecularly imprinted copolymer for selective and simultaneous determination of riboflavin, dopamine, and L-tryptophan

期刊: JOURNAL OF MOLECULAR RECOGNITION, 2023; 36 (10)

This research shows the exact detection of riboflavin (RF), dopamine (DA), and L-tryptophan (Trp) through molecularly imprinted polymer (MIP) based on......

Mechanistic aspects of binding of telomeric over parallel G-quadruplex with novel synthesized Knoevenagel condensate 4-nitrobenzylidene curcumin

期刊: JOURNAL OF MOLECULAR RECOGNITION, 2023; 36 (8)

The introduction of small ligands to stabilise G-quadruplex DNA structures is a promising method for developing anti-cancer drugs. It is challenging t......

Adsorption of Ibuprofen as a pharmaceutical pollutant from aqueous phase using zinc oxide nanoparticles: Green synthesis, batch adsorption, and biological activities

期刊: JOURNAL OF MOLECULAR RECOGNITION, 2023; 36 (7)

Recent interest has focused on the biosynthesis of metal nanoparticles (NPs), particularly from plants. The production of precipitate served as an ear......

Mechanics of leukemic T-cell

期刊: JOURNAL OF MOLECULAR RECOGNITION, 2023; 36 (7)

Cell mechanics is a factor that determines cell growth, migration, proliferation, or differentiation, as well as trafficking inside the cytoplasm and ......

Cheminformatics and systems pharmacology approaches to unveil the potential plant bioactives to combat COVID-19

期刊: JOURNAL OF MOLECULAR RECOGNITION, 2023; 36 (10)

COVID-19 was a global pandemic in the year 2020. Several treatment options failed to cure the disease. Thus, plant-based medicines are becoming a tren......

Chalcones bearing nitrogen-containing heterocyclics as multi-targeted inhibitors: Design, synthesis, biological evaluation and molecular docking studies

期刊: JOURNAL OF MOLECULAR RECOGNITION, 2023; 36 (7)

In this work, a series of chalcones (1a-d, 2a-d, 3a-d, 4a-d, and 5a-d) were designed and synthesized by Claisen-Schmidt condensation. Also, their chem......

Design and development of novel potential inhibitors of the human USP21 enzyme using a pharmacophore-based virtual screening technique

期刊: JOURNAL OF MOLECULAR RECOGNITION, 2023; 36 (7)

An overexpression and increase have been observed in the concentration and activity of the ubiquitin-specific protease 21 (USP21) enzyme in many cance......

Synthesis of new compounds bearing methyl sulfonyl pharmacophore as selective COX-2 inhibitor

期刊: JOURNAL OF MOLECULAR RECOGNITION, 2023; 36 (7)

Cyclooxygenase, also known as prostaglandin H2 synthase (PGH2), is one of the most important enzymes in pharmacology because inhibition of COX is the ......

β-Lactoglobulin variants as potential carriers of pramoxine: Comprehensive structural and biophysical studies

期刊: JOURNAL OF MOLECULAR RECOGNITION, 2023; 36 (10)

beta-Lactoglobulin (BLG) is a member of the lipocalin family. As other proteins from this group, BLG can be modified to bind specifically compounds of......

Porphyrin-based ligand interaction with G-quadruplex: Metal cation effects

期刊: JOURNAL OF MOLECULAR RECOGNITION, 2023; 36 (8)

The G-quadruplex planar-ligand complex is used to detect heavy metal cations such as Ag+, Cu2+, Pb2+, Hg2+, organic molecules, nucleic acids, and prot......

Gossypin mitigates oxidative damage by downregulating the molecular signaling pathway in oleic acid-induced acute lung injury

期刊: JOURNAL OF MOLECULAR RECOGNITION, 2023; 36 (11)

One of the leading causes of acute lung injury, which is linked to a high death rate, is pulmonary fat embolism. Increases in proinflammatory cytokine......

In silico identification and analysis of potential inhibitors for acid phosphatase, HppA from Helicobacter pylori

期刊: JOURNAL OF MOLECULAR RECOGNITION, 2023; 36 (9)

Helicobacter pylori is the most common cause of gastric ulcers and is associated with gastric cancer. The enzyme HppA of class C nonspecific acid phos......

Green synthesis of silver nanoparticles mediated Azadirachta indica extract and study of their characterization, molecular docking, and antibacterial activity

期刊: JOURNAL OF MOLECULAR RECOGNITION, 2023; 36 (10)

The green production of silver nanoparticles (AgNPs) produces AgNPs with minimum influence on the environment by using plant components such as alkalo......

Biphasic reinforcement of nascent adhesions by vinculin

期刊: JOURNAL OF MOLECULAR RECOGNITION, 2023; ()

Vinculin is an integral component of integrin adhesions, where it functions as a molecular clutch coupling intracellular contraction to the extracellu......

Advances in mechanical biomarkers

期刊: JOURNAL OF MOLECULAR RECOGNITION, 2023; 36 (8)

Mechanical biomarkers distinguish health conditions through quantitative mechanical measurements. The emergence and establishment of nanotechnology in......

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