筛选条件 共查询到500条结果
排序方式
LncRNA DSCAM-AS1: A Pivotal Therapeutic Target in Cancer

期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023; 23 (5)

Background LncRNAs are an emerging category of non-coding RNAs. LncRNAs are usually greater than 200 nucleotides in length and do not possess protein ......

Centrosome Clustering & Chemotherapy

期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023; 23 (4)

Centrosome abnormalities are the hallmark of cancer. How it affects tumorigenesis is still a mystery. However, the presence of more than two centrosom......

Anti-Tubercular Activity of Pyrazinamide Conjugates: Synthesis and Structure-Activity Relationship Studies

期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023; 23 (6)

Tuberculosis (TB) is an airborne infection caused by the bacteria Mycobacterium Tuberculosis (MTB). It mainly affects the lungs and causes severe coug......

A Comprehensive Review on PCSK9 as Mechanistic Target Approach in Cancer Therapy

期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023; 23 (1)

PCSK9 is a strongly expressed protein in the liver and brain that binds to the LDLR and regulates cholesterol in the liver effectively. Other receptor......

Targeting Virus-Induced Reprogrammed Cell Metabolism via Glycolytic Inhibitors: An Effective Therapeutic Approach Against SARS-CoV-2

期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023; 23 (2)

Reprogrammed cell metabolism has been observed in a wide range of virally infected cells. Viruses do not have their metabolism; they rely on the cellu......

Bioactive Furanyl- or Thienyl-Substituted Nucleobases, Nucleosides and Their Analogues

期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023; 23 (5)

Five-membered heterocycles, including furan and thiophene, play a prominent role in drug design as structural units of bioactive molecules. This revie......

Potential of Phytomolecules in Alliance with Nanotechnology to Surmount the Limitations of Current Treatment Options in the Management of Osteoarthritis

期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023; 23 (9)

Osteoarthritis (OA), a chronic degenerative musculoskeletal disorder, progressively increases with age. It is characterized by progressive loss of hya......

Association between Chlamydia trachomatis Infection and Male Infertility: A Systematic Review and Meta-Analysis

期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023; 23 (6)

Background Chlamydia trachomatis infection is one of the most common sexually transmitted diseases. There is widespread evidence in recent years that ......

Antiviral Activity of Pyrimidine Containing Compounds: Patent Review

期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023; 23 (7)

Viruses are still the most prevalent infectious pathogens on a worldwide scale, with many of them causing life-threatening illnesses in humans. Influe......

A Short Review of Antimalarial Compounds with Sulfonamide Moiety

期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023; 23 (21)

Malaria is a public health problem that causes thousands of deaths, primarily in children in African regions. Artemisinin-based combination therapies ......

Irisin and Energy Metabolism and the Role of Irisin on Metabolic Syndrome

期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023; 23 (20)

Irisin is a thermogenic hormone that leads to causes energy expenditure by increasing brown adipose tissue (BAT). This protein hormone that enables th......

Inhibitors Targeting Hepatitis C Virus (HCV) Entry

期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023; 23 (11)

Infections caused by the Hepatitis C virus (HCV) affect around 70 million people worldwide, leading to serious liver problems, such as fibrosis, steat......

The Role of Genetics and Synergistic Effect of Targeting Common Genetic Mutations in Acute Lymphoblastic Leukemia (ALL)

期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023; 23 (14)

Increasing concern regarding non-treatment and relapse in Acute Lymphoblastic Leukemia (ALL) among children and adults has attracted the attention of ......

Structural Perspective of Benzophenones Targeting Tubulin as Anticancer Agents

期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023; 23 (1)

Cancer is the leading cause of death and the most significant determinant of life expectancy in almost every country in this twenty-first century. Acc......

Alternative Methods for Pulmonary-Administered Drugs Metabolism: A Breath of Change

期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023; 23 (2)

Prediction of pulmonary metabolites following inhalation of a locally acting pulmonary drug is essential to the successful development of novel inhale......

共500条页码: 1/34页15条/页