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Short-Chain Fatty Acids Attenuate Renal Fibrosis and Enhance Autophagy of Renal Tubular Cells in Diabetic Mice Through the HDAC2/ULK1 Axis

期刊: ENDOCRINOLOGY AND METABOLISM, 2022; 37 (3)

Background: This study investigated the effect of short-chain fatty acids (SCFAs) on diabetes in a mouse model. Methods: Autophagy in Akita mice and s......

JIF:2.906

Fancd2os Reduces Testosterone Production by Inhibiting Steroidogenic Enzymes and Promoting Cellular Apoptosis in Murine Testicular Leydig Cells

期刊: ENDOCRINOLOGY AND METABOLISM, 2022; 37 (3)

Background: It is well-established that serum testosterone in men decreases with age, yet the underlying mechanism of this change remains elusive. Met......

JIF:2.906

Developmental Hypothyroidism Influences the Development of the Entorhinal-Dentate Gyrus Pathway of Rat Offspring

期刊: ENDOCRINOLOGY AND METABOLISM, 2022; 37 (2)

Background: Developmental hypothyroidism impairs learning and memory in offspring, which depend on extensive neuronal circuits in the entorhinal corte......

JIF:2.906

Inhibition of miR-146a-5p and miR-8114 in Insulin- Secreting Cells Contributes to the Protection of Melatonin against Stearic Acid-Induced Cellular Senescence by Targeting Mafa

期刊: ENDOCRINOLOGY AND METABOLISM, 2022; 37 (6)

Background: Chronic exposure to elevated levels of saturated fatty acids results in pancreatic (3-cell senescence. However, targets and effective agen......

JIF:2.906

Insights from a Prospective Follow-up of Thyroid Function and Autoimmunity among COVID-19 Survivors

期刊: ENDOCRINOLOGY AND METABOLISM, 2021; 36 (3)

Background: The occurrence of Graves' disease and Hashimoto thyroiditis after coronavirus disease 2019 (COVID-19) raised concerns that severe acute re......

Role of PCSK9 Inhibitors in Patients with Familial Hypercholesterolemia

期刊: ENDOCRINOLOGY AND METABOLISM, 2021; 36 (2)

Patients with familial hypercholesterolemia (FH) are at high or very high risk for cardiovascular disease. Those with heterozygous FH (HeFH) often do ......

The Positive Association between Subclinical Hypothyroidism and Newly-Diagnosed Hypertension Is More Explicit in Female Individuals Younger than 65

期刊: ENDOCRINOLOGY AND METABOLISM, 2021; 36 (4)

Background: Subclinical hypothyroidism (SCH) is the most common thyroid dysfunction, and its relationship with blood pressure (BP) has been controvers......

Development of a Non-Invasive Liver Fibrosis Score Based on Transient Elastography for Risk Stratification in Patients with Type 2 Diabetes

期刊: ENDOCRINOLOGY AND METABOLISM, 2021; 36 (1)

Background: In non-alcoholic fatty liver disease (NAFLD), transient elastography (TE) is an accurate non-invasive method to identify patients at risk ......

Molecular Correlates and Nuclear Features of Encapsulated Follicular-Patterned Thyroid Neoplasms

期刊: ENDOCRINOLOGY AND METABOLISM, 2021; 36 (1)

Background: Assessing nuclear features is diagnostically challenging in the aspect of thyroid pathology. The aim of this study was to determine whethe......

Precision Therapy in Acromegaly Caused by Pituitary Tumors: How Close Is It to Reality?

期刊: ENDOCRINOLOGY AND METABOLISM, 2020; 35 (2)

Acromegaly presents with an enigmatic range of symptoms and comothidities caused by chronic and progressive growth hormone elevations, commonly due to......

Updates in the Pathologic Classification of Thyroid Neoplasms: A Review of the World Health Organization Classification

期刊: ENDOCRINOLOGY AND METABOLISM, 2020; 35 (4)

Advances in medical sciences and evidence-based medicine have led to momentous changes in classification and management of thyroid neoplasms. Much pro......

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