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Assembly of model postsynaptic densities involves interactions auxiliary to stoichiometric binding

期刊: BIOPHYSICAL JOURNAL, 2022; 121 (1)

The assembly of functional biomolecular condensates often involves liquid-liquid phase separation (LLPS) of proteins with multiple modular domains, wh......

JIF:3.452

Understanding the molecular mechanism of endothelin ETA receptor selecting isopeptides endothelin-1 and-3

期刊: BIOPHYSICAL JOURNAL, 2022; 121 (13)

Endothelin-1 and -3 (ET1 and ET3) are potent vasoconstricting isopeptides that are involved in the pathophysiology of various diseases, such as cardio......

JIF:3.452

Molecular mechanism of CD44 homodimerization modulated by palmitoylation and membrane environments

期刊: BIOPHYSICAL JOURNAL, 2022; 121 (14)

The homodimerization of CD44 plays a key role in an intercellular-to-extracellular signal transduction and tumor progression. Acylated modification an......

JIF:3.452

Effects of cholesterol and PIP2 on interactions between glycophorin A and Band 3 in lipid bilayers

期刊: BIOPHYSICAL JOURNAL, 2022; 121 (11)

In the erythrocyte membrane, the interactions between glycophorin A (GPA) and Band 3 are associated strongly with the biological function of the membr......

JIF:3.452

Organizations of melittin peptides after spontaneous penetration into cell membranes

期刊: BIOPHYSICAL JOURNAL, 2022; 121 (22)

The antimicrobial peptide, melittin, is a potential next-generation antibiotic because melittin can spontaneously form pores in bacterial cell membran......

JIF:3.452

Two-phase dynamics of DNA supercoiling based on DNA polymer physics

期刊: BIOPHYSICAL JOURNAL, 2022; 121 (4)

DNA supercoils are generated in genome regulation processes such as transcription and replication and provide mechanical feedback to such processes. U......

JIF:3.452

High turnover and rescue effect of XRCC1 in response to heavy charged particle radiation

期刊: BIOPHYSICAL JOURNAL, 2022; 121 (8)

The DNA damage response is a highly orchestrated process. The involvement of the DNA damage response factors in DNA damage response depends on their b......

JIF:3.452

Elasticity-associated rebinding rate of molecular bonds between soft elastic media

期刊: BIOPHYSICAL JOURNAL, 2022; 121 (12)

A quantitative understanding of how cells interact with their extracellular matrix via molecular bonds is fundamental for many important processes in ......

JIF:3.452

Stability profile of the neuronal SNARE complex reflects its potency to drive fast membrane fusion

期刊: BIOPHYSICAL JOURNAL, 2022; 121 (16)

Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) form the SNARE com-plex to mediate most fusion events of the secretory......

JIF:3.452

Deciphering the mechanisms of HPV E6 mutations in the destabilization of E6/E6AP/p53 complex

期刊: BIOPHYSICAL JOURNAL, 2022; 121 (9)

In epithelial tumors, oncoprotein E6 binds with the ubiquitin ligase E6AP to form E6/E6AP heterodimer; then this heterodimer recruits p53 to form E6/E......

JIF:3.452

Mechanical regulation of the helicase activity of Zika virus NS3

期刊: BIOPHYSICAL JOURNAL, 2022; 121 (24)

Zika virus (ZIKV) is a positive-sense single-stranded RNA virus that infects humans and can cause birth defects and neurological disorders. Its non-st......

JIF:3.452

Excited-state dynamics of all-trans protonated retinal Schiff base in CRABPII-based rhodopsin mimics

期刊: BIOPHYSICAL JOURNAL, 2022; 121 (21)

The rhodopsin mimic is a chemically synthetized complex with retinyl Schiff base (RSB) formed between pro-tein and the retinal chromophore that can mi......

JIF:3.452

Active chemo-mechanical feedbacks dictate the collective migration of cells on patterned surfaces

期刊: BIOPHYSICAL JOURNAL, 2022; 121 (7)

Recent evidence has demonstrated that, when cultured on micro-patterned surfaces, living cells can move in a coordinated manner and form distinct migr......

JIF:3.452

Observation of broken detailed balance in polymorphic transformation of bacterial flagellar filament

期刊: BIOPHYSICAL JOURNAL, 2022; 121 (12)

Living systems operate far from thermodynamic equilibrium, which usually manifests as broken detailed balance at the molecular scale. At larger scales......

JIF:3.452

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