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lncRNA XIST induces A beta accumulation and neuroinflammation by the epigenetic repression of NEP in Alzheimer's disease

期刊: JOURNAL OF NEUROGENETICS, 2022; 36 (1)

Alzheimer's disease (AD) is the leading cause of dementia globally, but effective treatment is lacking. We aimed to explore lncRNA XIST role in AD and......

JIF:1.068

Knockdown of PHLDA2 promotes apoptosis and autophagy of glioma cells through the AKT/mTOR pathway

期刊: JOURNAL OF NEUROGENETICS, 2022; 36 (2-3)

Pleckstrin homology like domain family A member 2 (PHLDA2) is an imprinted gene expressed in placenta and has been shown to be associated with tumor p......

JIF:1.068

Reduction of the alpha-synuclein expression promotes slowing down early neuropathology development in the Drosophila model of Parkinson's disease

期刊: JOURNAL OF NEUROGENETICS, 2022; 36 (1)

Parkinson's disease (PD) is a neurodegenerative disease characterised by the formation of Lewy bodies and progressive loss of dopaminergic (DA) neuron......

JIF:1.068

LncRNA GAS5 promotes epilepsy progression through the epigenetic repression of miR-219, in turn affecting CaMKII gamma/NMDAR pathway

期刊: JOURNAL OF NEUROGENETICS, 2022; 36 (1)

It has been widely reported that dysregulated long-chain noncoding RNAs (lncRNAs) are closely associated with epilepsy. This study aimed to probe the ......

JIF:1.068

Mechano-gated channels in C. elegans

期刊: JOURNAL OF NEUROGENETICS, 2020; 34 (3-4)

Mechanosensation such as touch, hearing and proprioception, is functionally regulated by mechano-gated ion channels through the process of transductio......

Understanding neurobehavioral genetics of zebrafish

期刊: JOURNAL OF NEUROGENETICS, 2020; 34 (2)

Due to its fully sequenced genome, high genetic homology to humans, external fertilization, fast development, transparency of embryos, low cost and ac......

Oxytocin ameliorates bone cancer pain by suppressing toll-like receptor 4 and proinflammatory cytokines in rat spinal cord

期刊: JOURNAL OF NEUROGENETICS, 2020; 34 (2)

Bone cancer pain is considered to be mechanistically unique compared with inflammatory or neuropathic pain states. Toll-like receptor 4 (TLR4) is a tr......

Gene polymorphisms associated with temperament

期刊: JOURNAL OF NEUROGENETICS, 2017; 31 (1-2)

When individuals are exposed to stressful environmental challenges, the response varies widely in one or more of three components: psychology, behavio......

JIF:1.54

Overexpression of U1 snRNA induces decrease of U1 spliceosome function associated with Alzheimer's disease

期刊: JOURNAL OF NEUROGENETICS, 2017; 31 (4)

We recently reported that presenilin-1 (PS1) induced an increase of U1 snRNA expression accompanied with the change of amyloid precursor protein expre......

JIF:1.54

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