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Decoding DNA methylation in epigenetics of multiple myeloma

期刊: BLOOD REVIEWS, 2022; 51 ()

Dysregulation of DNA methylation in B cells has been observed during their neoplastic transformation and therefore closely associated with various B-c......

JIF:7.587

Cell therapy of chronic lymphocytic leukaemia: Transplants and chimeric antigen receptor (CAR)-T cells

期刊: BLOOD REVIEWS, 2022; 51 ()

There is substantial progress in the therapy of chronic lymphocytic leukaemia (CLL), much of it the result of new drug development. As such the defini......

JIF:7.587

One arrow for two targets: potential co-treatment regimens for lymphoma and HIV

期刊: BLOOD REVIEWS, 2022; 55 ()

In 2007, an HIV-infected individual (Berlin patient) underwent two allogeneic haematopoietic stem cell transplantations (allo-HSCTs) from a donor with......

JIF:7.587

Metabolic regulation of the bone marrow microenvironment in leukemia

期刊: BLOOD REVIEWS, 2021; 48 ()

Most leukemia patients experience little benefit from immunotherapy, in part due to the immunosuppressive bone marrow microenvironment. Various metabo......

Arterial thrombosis in antiphospholipid syndrome (APS): Clinical approach and treatment. A systematic review

期刊: BLOOD REVIEWS, 2021; 48 ()

Thrombotic Antiphospholipid Syndrome (APS) is a condition affecting young individuals in whom a thromboembolic event occurs in the presence of circula......

The impact of ABO blood group on COVID-19 infection risk and mortality: A systematic review and meta-analysis

期刊: BLOOD REVIEWS, 2021; 48 ()

The 2019 coronavirus disease (COVID-19) has become a global pandemic. Several studies report that ABO blood group polymorphism may be related to COVID......

From multi-target anticoagulants to DOACs, and intrinsic coagulation factor inhibitors

期刊: BLOOD REVIEWS, 2020; 39 ()

From the 1940s to 1990s, heparin and warfarin have been the main anticoagulants for the prevention and treatment of thrombotic events. Since then, LMW......

Apoptosis signaling and BCL-2 pathways provide opportunities for novel targeted therapeutic strategies in hematologic malignances

期刊: BLOOD REVIEWS, 2018; 32 (1)

Apoptosis is an essential biological process involved in tissue homeostasis and immunity. Aberrations of the two main apoptotic pathways, extrinsic an......

JIF:6.13

Unrelated donor umbilical cord blood transplant versus unrelated hematopoietic stem cell transplant in patients with acute leukemia: A meta-analysis and systematic review

期刊: BLOOD REVIEWS, 2018; 32 (3)

Acute leukemia is a global disease with a poor prognosis for many patients. While an increasing number of patients with acute leukemia are being treat......

JIF:6.13

NF-kappa B signaling pathway and its potential as a target for therapy in lymphoid neoplasms

期刊: BLOOD REVIEWS, 2017; 31 (2)

The NF-kappa B pathway, a critical regulator of apoptosis, plays a key role in many normal cellular functions. Genetic alterations and other mechanism......

JIF:6.6

Treatment of acute myeloid leukemia in the next decade - Towards real-time functional testing and personalized medicine

期刊: BLOOD REVIEWS, 2017; 31 (6)

Information arising from next generation sequencing of leukemia genome has shed important light on the heterogeneous and combinatorial driver events i......

JIF:6.6

Light chain amyloidosis: Where are the light chains from and how they play their pathogenic role?

期刊: BLOOD REVIEWS, 2017; 31 (4)

Amyloid light-chain (AL) amyloidosis is a plasma-cell dyscrasia, as well as the most common type of systematic amyloidosis. Pathogenic plasma cells th......

JIF:6.6

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