期刊: BLOOD REVIEWS, 2022; 51 ()
Dysregulation of DNA methylation in B cells has been observed during their neoplastic transformation and therefore closely associated with various B-c......
期刊: BLOOD REVIEWS, 2022; 51 ()
There is substantial progress in the therapy of chronic lymphocytic leukaemia (CLL), much of it the result of new drug development. As such the defini......
期刊: BLOOD REVIEWS, 2022; 55 ()
In 2007, an HIV-infected individual (Berlin patient) underwent two allogeneic haematopoietic stem cell transplantations (allo-HSCTs) from a donor with......
期刊: BLOOD REVIEWS, 2021; 48 ()
Most leukemia patients experience little benefit from immunotherapy, in part due to the immunosuppressive bone marrow microenvironment. Various metabo......
期刊: BLOOD REVIEWS, 2021; 48 ()
Thrombotic Antiphospholipid Syndrome (APS) is a condition affecting young individuals in whom a thromboembolic event occurs in the presence of circula......
期刊: BLOOD REVIEWS, 2021; 48 ()
The 2019 coronavirus disease (COVID-19) has become a global pandemic. Several studies report that ABO blood group polymorphism may be related to COVID......
期刊: BLOOD REVIEWS, 2020; 39 ()
From the 1940s to 1990s, heparin and warfarin have been the main anticoagulants for the prevention and treatment of thrombotic events. Since then, LMW......
期刊: BLOOD REVIEWS, 2018; 32 (1)
Apoptosis is an essential biological process involved in tissue homeostasis and immunity. Aberrations of the two main apoptotic pathways, extrinsic an......
期刊: BLOOD REVIEWS, 2018; 32 (3)
Acute leukemia is a global disease with a poor prognosis for many patients. While an increasing number of patients with acute leukemia are being treat......
期刊: BLOOD REVIEWS, 2017; 31 (2)
The NF-kappa B pathway, a critical regulator of apoptosis, plays a key role in many normal cellular functions. Genetic alterations and other mechanism......
期刊: BLOOD REVIEWS, 2017; 31 (6)
Information arising from next generation sequencing of leukemia genome has shed important light on the heterogeneous and combinatorial driver events i......
期刊: BLOOD REVIEWS, 2017; 31 (4)
Amyloid light-chain (AL) amyloidosis is a plasma-cell dyscrasia, as well as the most common type of systematic amyloidosis. Pathogenic plasma cells th......