期刊： JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (11)
While variants of noncoding RNAs (ncRNAs) have been experimentally validated as a new class of biomarkers and drug targets, the discovery and interpre......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (18)
Somatic mutations in the PRKACA gene encoding the catalytic alpha subunit of protein kinase A (PKA-C) are responsible for cortisol-producing adrenocor......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (15)
Ion conduction is an essential function for electrical activity in all organisms. The non-selective ion channel NaK was previously shown to adopt two ......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (17)
Transient receptor potential (TRP) ion channels are a super-family of ion channels that mediate transmembrane cation flux with polymodal activation, r......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (10)
Genome-wide protein-protein interaction (PPI) determination remains a significant unsolved problem in structural biology. The difficulty is twofold si......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (14)
Pontin is a AAA+ ATPase protein that has functions in various biological contexts including gene transcription regulation, chromatin remodeling, DNA d......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (13)
The outer membrane (OM) of Gram-negative bacteria, which consists of lipopolysaccharides (LPS) in the outer leaflet and phospholipids (PLs) in the inn......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (13)
The bacterial flagellum consists of a long extracellular filament that is rotated by a motor embedded in the cell envelope. While flagellar assembly h......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (11)
As a key region, promoter plays a key role in transcription regulation. A eukaryotic promoter database called EPD has been constructed to store eukary......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (13)
DEP domain containing mTOR-interacting protein (DEPTOR) plays pivotal roles in regulating metabolism, growth, autophagy and apoptosis by functions as ......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (1)
B cells have recently emerged as playing regulatory role in autoimmune diseases. We have previously demonstrated that human peripheral blood CD19(+)CD......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (2)
Na+/H+ antiporters are a category of ubiquitous transmembrane proteins with various important physiological roles in almost all living organisms rangi......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (2)
The Tuberous Sclerosis Complex (TSC) protein complex (TSCC), comprising TSC1, TSC2, and TBC1 D7, is widely recognised as a key integration hub for cel......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (2)
Amyloid aggregation of tau protein is implicated in neurodegenerative diseases, yet its facilitating factors are poorly understood. Recently, tau has ......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2021; 433 (3)
Regulation of bacterial stress responding sigma(S) is a sophisticated process and mediated by multiple interacting partners. Controlled proteolysis of......
