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Hemophagocytic Lymphohistiocytosis Secondary to Juvenile Myelomonocytic Leukemia: A Case Report and Review of the Literature

期刊: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2022; 44 (2)

Rationale: Juvenile myelomonocytic leukemia (JMML) is a rare hematopoietic disorder, which is more rarely accompanied by monosomy 5 or deletion of the......

JIF:1.044

Longer Time Intervals From Symptom Onset to Diagnosis Affect the Overall Survival in Children With Acute Lymphoblastic Leukemia

期刊: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2022; 44 (6)

Background: Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Early diagnosis and timely treatment are essential for effective c......

JIF:1.044

Hemophagocytic Lymphohistiocytosis in Langerhans Cell Histiocytosis: A Case Series and Literature Review

期刊: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2022; 44 (1)

Langerhans cell histiocytosis (LCH) is characterized pathologically by langerin-positive (CD207(+)) dendritic cell proliferation and is considered by ......

JIF:1.044

Effect of BCG HSP70 Gene Transfection on Dendritic Cells Derived From Bone Marrow in Children With Acute Leukemia

期刊: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2022; 44 (6)

Objectives: In this study, immature dendritic cells (imDCs) were transfected with the Bacille Calmette-Guerin (BCG) heat shock protein 70 (HSP70) gene......

JIF:1.044

Treatment of Relapsed and Refractory ALK-Positive Anaplastic Large Cell Lymphoma With ALK-Specific Tyrosine Kinase Inhibitor in Children: A Case Series

期刊: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2022; 44 (1)

Relapsed and refractory ALK-positive anaplastic large cell lymphoma (ALCL) has a poor prognosis. In this report, we present 3 relapsed/refractory pedi......

JIF:1.044

Secondary Leukemia in a Patient With EBV-HLH Carrying Heterozygous STXBP2 Variant

期刊: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2022; 44 (2)

Hemophagocytic lymphohistiocytosis (HLH) is a symptom with severe systemic hyperinflammation. A 26-month-old male presented with Epstein-Barr virus as......

JIF:1.044

Association Between SHMT1 rs1979277 Polymorphism and Risk of Acute Lymphoblastic Leukemia: A Systematic Review and Meta-analysis

期刊: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2022; 44 (3)

Objectives: The aim of this study was to explore the potential association the cytosolic serine hydroxy methyltransferase (SHMT1) rs1979277 polymorphi......

JIF:1.044

Clinical Features and Prognostic Factors of Early Outcome in Pediatric Hemophagocytic Lymphohistiocytosis: A Retrospective Analysis of 227 Cases

期刊: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2022; 44 (1)

Hemophagocytic lymphohistiocytosis (HLH) is a rare but life-threatening clinical syndrome in children, and the knowledge of it is still limited. Two h......

JIF:1.044

The Status of Pediatric Patients With Hematologic Malignancy During COVID-19 Pandemic in Wuhan City, China

期刊: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2022; 44 (1)

Data regarding the epidemiologic characteristics and clinical features of pediatric hematologic patients are limited in this corona virus disease 2019......

JIF:1.044

IKZF1 Rs4132601 Polymorphism and Susceptibility to Acute Lymphocytic Leukemia in Children: A Meta-analysis

期刊: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2022; 44 (1)

Background: Many studies have shown that IKAROS family zinc finger 1 (IKZF1) rs4132601 polymorphism is strongly linked to acute lymphoblastic leukemia......

JIF:1.044

Evaluation of Inflammatory Biomarkers in Pediatric Hematology-Oncology Patients With Bloodstream Infection

期刊: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2021; 43 (4)

Bloodstream infection (BSI) is a serious complication in pediatric hematology-oncology patients. To evaluate the clinical significance of C-reactive p......

Hemolytic Disease of the Fetus and Newborn Caused by Anti-Group A IgG From a Group B Mother

期刊: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2021; 43 (6)

ABO incompatibility has emerged as the premier reason for hemolytic disease of the fetus and newborn (HDFN). It always occurs in the offspring of bloo......

Morphologic and Immunophenotypic Differences in Juvenile Myelomonocytic Leukemias With CBL and Other Canonical RAS-pathway Gene Mutations: A Single Institutional Experience

期刊: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2021; 43 (6)

The diagnostic criteria for juvenile myelomonocytic leukemia have recently been revised to include clinical findings and RAS-pathway gene mutations pe......

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