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In silico T cell epitope identification for SARS-CoV-2: Progress and perspectives

期刊: ADVANCED DRUG DELIVERY REVIEWS, 2021; 171 ()

Growing evidence suggests that T cells may play a critical role in combating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Hence, COVI......

Particle engineering principles and technologies for pharmaceutical biologics

期刊: ADVANCED DRUG DELIVERY REVIEWS, 2021; 174 ()

The global market of pharmaceutical biologics has expanded significantly during the last few decades. Currently, pharmaceutical biologic products cons......

Pharmaceutical electrospinning and 3D printing scaffold design for bone regeneration

期刊: ADVANCED DRUG DELIVERY REVIEWS, 2021; 174 ()

Bone regenerative engineering provides a great platform for bone tissue regeneration covering cells, growth factors and other dynamic forces for fabri......

Non-viral nanoparticles for RNA interference: Principles of design and practical guidelines

期刊: ADVANCED DRUG DELIVERY REVIEWS, 2021; 174 ()

Ribonucleic acid interference (RNAi) is an innovative treatment strategy for a myriad of indications. Non-viral synthetic nanoparticles (NPs) have dra......

Dynamic nanoassembly-based drug delivery system (DNDDS): Learning from nature

期刊: ADVANCED DRUG DELIVERY REVIEWS, 2021; 175 ()

Dynamic nanoassembly-based drug delivery system (DNDDS) has evolved from being a mere curiosity to emerging as a promising strategy for high-performan......

Antimicrobial peptides towards clinical application: Delivery and formulation

期刊: ADVANCED DRUG DELIVERY REVIEWS, 2021; 175 ()

Antimicrobial peptides hold promise to supplement small molecules antibiotics and combat the multidrug resistant microbes. There are however technical......

Understanding the interactions between inorganic-based nanomaterials and biological membranes

期刊: ADVANCED DRUG DELIVERY REVIEWS, 2021; 175 ()

The interactions between inorganic-based nanomaterials (NMs) and biological membranes are among the most important phenomena for developing NM-based t......

Regulation of in vivo delivery of nanomedicines by herbal medicines

期刊: ADVANCED DRUG DELIVERY REVIEWS, 2021; 174 ()

ABSTR A C T Nanomedicines are of increasing scrutiny due to their improved efficacy and/or mitigated side effects. They can be integrated with many ot......

alpha-Amino acid N-carboxyanhydride (NCA)-derived synthetic polypeptides for nucleic acids delivery

期刊: ADVANCED DRUG DELIVERY REVIEWS, 2021; 171 ()

In recent years, gene therapy has come into the spotlight for the prevention and treatment of a wide range of diseases. Polypeptides have been widely ......

Tumor microenvironment remodeling-based penetration strategies to amplify nanodrug accessibility to tumor parenchyma q

期刊: ADVANCED DRUG DELIVERY REVIEWS, 2021; 172 ()

Remarkable advances in nano delivery systems have provided new hope for tumor prevention, diagnosis and treatment. However, only limited clinical ther......

Dry powder pharmaceutical biologics for inhalation therapy

期刊: ADVANCED DRUG DELIVERY REVIEWS, 2021; 172 ()

Therapeutic biologics such as genes, peptides, proteins, virus and cells provide clinical benefits and are becoming increasingly important tools in re......

Recent trends in drug-delivery systems for the treatment of diabetic retinopathy and associated fibrosis

期刊: ADVANCED DRUG DELIVERY REVIEWS, 2021; 173 ()

Diabetic retinopathy is a frequent microvascular complication of diabetes and a major cause of visual impairment. In advanced stages, the abnormal neo......

Peptide-based supramolecular hydrogels for local drug delivery

期刊: ADVANCED DRUG DELIVERY REVIEWS, 2021; 174 ()

Peptide-based supramolecular hydrogels have shown great promise as drug delivery systems (DDSs) because of their excellent biocompatibility, biodegrad......

Vaginal drug delivery approaches for localized management of cervical cancer

期刊: ADVANCED DRUG DELIVERY REVIEWS, 2021; 174 ()

Cervical cancer or cervical intraepithelial neoplasia (CIN) remain a major public health problem among women globally. Traditional methods such as sur......

Dynamic nanoassemblies for imaging and therapy of neurological disorders

期刊: ADVANCED DRUG DELIVERY REVIEWS, 2021; 175 ()

The past decades have witnessed an increased incidence of neurological disorders (NDs) such as Alzheimer's disease, Parkinson's disease, Huntington's ......

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