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Establishment and histopathological study of patient-derived xenograft models and primary cell lines of epithelioid malignant peritoneal mesothelioma

期刊: EXPERIMENTAL ANIMALS, 2021; 70 (2)

Malignant peritoneal mesothelioma (MPM) is a rare malignancy with few experimental models. This study used the human surgical specimen to establish MP......

Cholinergic-rather than adrenergic-induced sweating play a role in developing and developed rat eccrine sweat glands

期刊: EXPERIMENTAL ANIMALS, 2021; 70 (2)

Both cholinergic and adrenergic stimulation can induce sweat secretion in human eccrine sweat glands, but whether cholinergic and adrenergic stimulati......

Impacts of ceftriaxone exposure during pregnancy on maternal gut and placental microbiota and its influence on maternal and offspring immunity in mice

期刊: EXPERIMENTAL ANIMALS, 2021; 70 (2)

This study aimed to investigate the association between microbiota found in the maternal gut and placenta, and whether ceftriaxone exposure during pre......

miR-374 improves cerebral ischemia reperfusion injury by targeting Wnt5a

期刊: EXPERIMENTAL ANIMALS, 2021; 70 (1)

To date, studies have demonstrated the potential functions of microRNAs in cerebral ischemia reperfusion (IR) injury. Herein, we established a middle ......

Comparison of the anatomical morphology of cervical vertebrae between humans and macaques: related to a spinal cord injury model

期刊: EXPERIMENTAL ANIMALS, 2021; 70 (1)

Non-human primates are most suitable for generating cervical experimental models, and it is necessary to study the anatomy of the cervical spine in no......

A high-fat diet and high-fat and high-cholesterol diet may affect glucose and lipid metabolism differentially through gut microbiota in mice

期刊: EXPERIMENTAL ANIMALS, 2021; 70 (1)

This study was conducted to investigate the effects of a high-fat diet (HFD) and high-fat and high-cholesterol diet (HFHCD) on glucose and lipid metab......

Effects of chitosan oligosaccharides on intestinal oxidative stress and inflammation response in heat stressed rats

期刊: EXPERIMENTAL ANIMALS, 2021; 70 (1)

This study was to verify the effects of chitosan oligosaccharides (COS) on intestinal integrity, oxidative status, and inflammatory response in a heat......

Chinese tree shrews as a primate experimental animal eligible for the study of alcoholic liver disease: characterization and confirmation by MRI

期刊: EXPERIMENTAL ANIMALS, 2020; 69 (1)

There has been a lack of suitable fatty liver models and characterization techniques for histopathological evaluation of alcoholic fatty liver (AFL). ......

Hemogram study of an artificially feeding tree shrew (Tupaia belangeri chinensis)

期刊: EXPERIMENTAL ANIMALS, 2020; 69 (1)

Systematic classification and determination of various cells in normal peripheral blood of artificially feeding Tupaia belangeri chinensis of differen......

A C1976Y missense mutation in the mouse Ip3r1 gene leads to short-term mydriasis and unfolded protein response in the iris constrictor muscles

期刊: EXPERIMENTAL ANIMALS, 2020; 69 (1)

Ip3r1 encodes an inositol 1,4,5-trisphosphate-responsive calcium channel. Mutations in the IP3R1 gene in humans may cause Gillespie syndrome (GS) typi......

Inhibition of long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 attenuates high glucose-induced cardiomyocyte apoptosis via regulation of miR-181a-5p

期刊: EXPERIMENTAL ANIMALS, 2020; 69 (1)

Diabetic cardiomyopathy (DCM) is one of the cardiovascular complications of diabetes mellitus independent of hypertension, coronary disease, and other......

Schisandrin ameliorates cognitive deficits, endoplasmic reticulum stress and neuroinflammation in streptozotocin (STZ)-induced Alzheimer's disease rats

期刊: EXPERIMENTAL ANIMALS, 2020; 69 (3)

Schisandrin, an active component extracted from Schisandra chinensis (Turcz.) Baill has been reported to alleviate the cognitive impairment in neurode......

Therapeutic effects of Co-Venenum Bufonis Oral Liquid on radiation-induced esophagitis in rats

期刊: EXPERIMENTAL ANIMALS, 2020; 69 (3)

To investigate the effects of Co-Venenum Bufonis Oral Liquid (cVBOL) on radiation-induced esophagitis in rats. Irradiation (30 Gy) with X-RAD 225 x-ra......

High fat diet induced obesity model using four strains of mice: Kunming, C57BL/6, BALB/c and ICR

期刊: EXPERIMENTAL ANIMALS, 2020; 69 (3)

High fat diet (HFD) treated mouse is widely used as experimental animal model for hyperlipidemia and hyperglycemia study. Many factors contribute to e......

Development of an effective microsatellite marker system to determine the genetic structure of Meriones meridianus populations

期刊: EXPERIMENTAL ANIMALS, 2020; 69 (2)

Understanding the genetic quality of the gerbil, Meriones meridianus, plays an important role in the study of medical biology. However, no effective s......

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