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Machine learning approach for the prediction of 30-day mortality in patients with sepsis-associated encephalopathy

期刊: BMC MEDICAL RESEARCH METHODOLOGY, 2022; 22 (1)

Objective Our study aimed to identify predictors as well as develop machine learning (ML) models to predict the risk of 30-day mortality in patients w......

JIF:4.402

The validity, reliability and feasibility of four instruments for assessing the consciousness of stroke patients in a neurological intensive care unit compared

期刊: BMC MEDICAL RESEARCH METHODOLOGY, 2022; 22 (1)

Background Early rehabilitation is the foundation for recovery for those admitted to an intensive care unit. Appropriate assessment of consciousness i......

JIF:4.402

A dose-finding design for phase I clinical trials based on Bayesian stochastic approximation

期刊: BMC MEDICAL RESEARCH METHODOLOGY, 2022; 22 (1)

Background Current dose-finding designs for phase I clinical trials can correctly select the MTD in a range of 30-80% depending on various conditions ......

JIF:4.402

Comparison of reference distributions acquired by direct and indirect sampling techniques: exemplified with the Pediatric Reference Interval in China (PRINCE) study

期刊: BMC MEDICAL RESEARCH METHODOLOGY, 2022; 22 (1)

Background Our study aimed to compare the reference distributions of serum creatinine and urea obtained by direct sampling technique and two indirect ......

JIF:4.402

Trial-level characteristics associate with treatment effect estimates: a systematic review of meta-epidemiological studies

期刊: BMC MEDICAL RESEARCH METHODOLOGY, 2022; 22 (1)

Background To summarize the up-to-date empirical evidence on trial-level characteristics of randomized controlled trials associated with treatment eff......

JIF:4.402

An innovative approach based on real-world big data mining for calculating the sample size of the reference interval established using transformed parametric and non-parametric methods

期刊: BMC MEDICAL RESEARCH METHODOLOGY, 2022; 22 (1)

Background Currently, the direct method is the main approach for establishment of reference interval (RI). However, only a handful of studies have des......

JIF:4.402

Estimation of average treatment effect based on a multi-index propensity score

期刊: BMC MEDICAL RESEARCH METHODOLOGY, 2022; 22 (1)

Background: Estimating the average effect of a treatment, exposure, or intervention on health outcomes is a primary aim of many medical studies. Howev......

JIF:4.402

Prediction of congenital heart disease for newborns: comparative analysis of Holt-Winters exponential smoothing and autoregressive integrated moving average models

期刊: BMC MEDICAL RESEARCH METHODOLOGY, 2022; 22 (1)

Objective To describe the temporal trend of the number of new congenital heart disease (CHD) cases among newborns in Jinhua from 2019 to 2020 and expl......

JIF:4.402

Relationship between patient experience and hospital readmission: system-level survey with deterministic data linkage method

期刊: BMC MEDICAL RESEARCH METHODOLOGY, 2022; 22 (1)

Background Linkage of public healthcare data provides powerful resources for studying from a comprehensive view of quality of care than information fo......

JIF:4.402

Multi-dimensional vulnerability analysis on catastrophic health expenditure among middle-aged and older adults with chronic diseases in China

期刊: BMC MEDICAL RESEARCH METHODOLOGY, 2022; 22 (1)

Objective Middle-aged and older adults are more likely to suffer from chronic diseases because of their particular health characteristics, which lead ......

JIF:4.402

Methodology and experiences of rapid advice guideline development for children with COVID-19: responding to the COVID-19 outbreak quickly and efficiently

期刊: BMC MEDICAL RESEARCH METHODOLOGY, 2022; 22 (1)

Background Rapid Advice Guidelines (RAG) provide decision makers with guidance to respond to public health emergencies by developing evidence-based re......

JIF:4.402

Short-form development of the specific module of the QLICD-CRF(V2.0) for assessing the quality of life of patients with chronic renal failure

期刊: BMC MEDICAL RESEARCH METHODOLOGY, 2022; 22 (1)

Background A short instrument would enhance the viability of a study. Therefore, we aimed to shorten the specific module (SPD-10) of the Quality of Li......

JIF:4.402

Generating real-world evidence compatible with evidence from randomized controlled trials: a novel observational study design applicable to surgical transfusion research

期刊: BMC MEDICAL RESEARCH METHODOLOGY, 2022; 22 (1)

BackgroundNumerous observational studies have revealed an increased risk of death and complications with transfusion, but this observation has not bee......

JIF:4.402

Interrater reliability estimators tested against true interrater reliabilities

期刊: BMC MEDICAL RESEARCH METHODOLOGY, 2022; 22 (1)

Background: Interrater reliability, aka intercoder reliability, is defined as true agreement between raters, aka coders, without chance agreement. It ......

JIF:4.402

Generative adversarial networks for imputing missing data for big data clinical research

期刊: BMC MEDICAL RESEARCH METHODOLOGY, 2021; 21 (1)

Background: Missing data is a pervasive problem in clinical research. Generative adversarial imputation nets (GAIN), a novel machine learning data imp......

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