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Quantitative Proteomic Study of Peripheral Blood Monocytes Identified Novel Genes Involved in Osteoporosis

期刊: CURRENT PROTEOMICS, 2021; 18 (4)

Objective: Osteoporosis (OP) is mainly characterized by low Bone Mineral Density (B MD) and microarchitectural deterioration of bone tissue. We perfor......

Proteomic Analysis of Differentially Expressed Proteins in Mycobacterium tuberculosis-Infected Macrophages

期刊: CURRENT PROTEOMICS, 2021; 18 (1)

Background: Mycobacterium tuberculosis (MTB) and Mycobacterium avium (MA) are intracellular parasitic bacteria. The biological characteristics of MA a......

Analysis of Oxaliplatin Resistance in Colorectal Cancer Cells by Combined Proteomics and Phosphoproteomic

期刊: CURRENT PROTEOMICS, 2021; 18 (2)

Background: Oxaliplatin(Oxa) is a major chemotherapy drug for colorectal cancer. However, drug resistance is a major cause of treatment failure for la......

Physiological and Biochemical Characteristics of Two Soybean Cultivars with Different Seed Vigor During Seed Physiological Maturity

期刊: CURRENT PROTEOMICS, 2021; 18 (1)

Background: The soybean seed's physiological maturity (R7) period is an extraordinary period for the formation of seed vigor. However, how proteins an......

ABC-Gly: Identifying Protein Lysine Glycation Sites with Artificial Bee Colony Algorithm

期刊: CURRENT PROTEOMICS, 2021; 18 (1)

Background: Glycation is a nonenzymatic post-translational modification process by attaching a sugar molecule to a protein or lipid molecule. It may i......

High Altitude Hypoxia

期刊: CURRENT PROTEOMICS, 2021; 18 (4)

The world's highest and largest altitude area is called the Qinghai-Tibetan plateau QTP, which harbors unique animal and plant species. Mammals that i......

Comparative Analysis of Skeleton Muscle Proteome Profile between Yak and Cattle Provides Insight into High-Altitude Adaptation

期刊: CURRENT PROTEOMICS, 2021; 18 (1)

Background: Mechanisms underlying yak adaptation to high-altitude environments have been investigated at the levels of morphology, anatomy, physiology......

Label-Free Mass Spectrometry-Based Plasma Proteomics Identified LY6D, DSC3, CDSN, SERPINB12, and SLURP1 as Novel Protein Biomarkers For Pulmonary Tuberculosis

期刊: CURRENT PROTEOMICS, 2021; 18 (1)

Aim: We aimed to identify new plasma biomarkers for the diagnosis of Pulmonary Tuberculosis (PTB). Background: Tuberculosis is an ancient infectious d......

Mass Spectrometry-Based Label-Free Quantitative Proteomic Analysis of CCl4-Induced Acute Liver Injury in Mice Intervened by Total Glycosides from Ligustri Lucidi Fructus

期刊: CURRENT PROTEOMICS, 2021; 18 (3)

Background: CCl4 Acute Liver Injury (ALI) is a classical model for experimental research. However, there are few reports involved in the fundamental r......

Analysis of the Non-Specific Binding Proteins in the RNA Pull-Down Experiment

期刊: CURRENT PROTEOMICS, 2021; 18 (2)

Background: To investigate the interactions between RNA and proteins is essential to understand how these macromolecule complexes exert their function......

A Refined Framework for Precision and Translational Proteomics in Clini-cal Research

期刊: CURRENT PROTEOMICS, 2021; 18 (4)

Most clinical related proteomic studies were aimed to screen potential biomarkers for clinical usage. However, it is known that only a few candidates ......

iTRAQ-based Quantitative Proteomic Analysis of Dural Tissues Reveals Upregulated Haptoglobin to be a Potential Biomarker of Moyamoya Disease

期刊: CURRENT PROTEOMICS, 2021; 18 (1)

Background: Moyamoya Disease (MMD) is a rare cerebrovascular disease with a high rate of disability and mortality. Immune reactions have been implicat......

Itraq-Based Proteomic Analysis of the Rat Pancreas Following Gastric By-pass Surgery

期刊: CURRENT PROTEOMICS, 2021; 18 (4)

Purpose: There are many people with type 2 Diabetes Mellitus (T2DM) worldwide. Roux-en-Y Gastric Bypass (RYGB) is an effective surgery for treating T2......

Role of Cervical Cancer Radiotherapy in the Expression of EGFR and p53 Gene

期刊: CURRENT PROTEOMICS, 2020; 17 (1)

Background: Cervical cancer arises from the cervix and it is the 3rd most diagnosed malignancy and a foremost cause of cancer-related death in females......

Characterization of Venoms of Deinagkistrodon acutus and Bungarus multicinctus Using Proteomics and Peptidomics

期刊: CURRENT PROTEOMICS, 2020; 17 (3)

Background: Deinagkistrodon acutus (D. acutus) and Bungarus multicinctus (B. multicinctus) as traditional medicines have been used for hundreds of yea......

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