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The clinical significance of glutathione peroxidase 2 in glioblastoma multiforme

期刊: TRANSLATIONAL NEUROSCIENCE, 2021; 12 (1)

Background - Glioblastoma multiforme (GBM) is the leading cause of death among adult brain cancer patients. Glutathione peroxidase 2 (GPX2), as a fact......

Calumenin contributes to epithelial-mesenchymal transition and predicts poor survival in glioma

期刊: TRANSLATIONAL NEUROSCIENCE, 2021; 12 (1)

Background - Calumenin (CALU) has been reported to be associated with invasiveness and metastasis in some malignancies. However, in glioma, the role o......

Vertebral plate and ligament composite laminoplasty in spinal cord tumor surgery: Analysis of 94 patients

期刊: TRANSLATIONAL NEUROSCIENCE, 2021; 12 (1)

Objectives - The aim of this study was to evaluate the value and long-term effect of laminectomy or laminoplasty in spinal cord tumor surgery. Patient......

Role of exosomal miRNAs in brain metastasis affected by radiotherapy

期刊: TRANSLATIONAL NEUROSCIENCE, 2021; 12 (1)

In oncogenesis and development of malignant tumor, microRNAs (miRNAs) regulate the complex gene expression associated with the tumor pathogenesis. Cur......

Vitamin D3 reduces hippocampal NR2A and anxiety in nicotine withdrawal mice

期刊: TRANSLATIONAL NEUROSCIENCE, 2021; 12 (1)

Nicotine withdrawal symptoms, mainly anxiety, cause high level of relapse rate after quitting smoking. Vitamin D supplementation has shown its potenti......

Intracerebral hemorrhage with tentorial herniation: Conventional open surgery or emergency stereotactic craniopuncture aspiration surgery?

期刊: TRANSLATIONAL NEUROSCIENCE, 2021; 12 (1)

Background -To observe the therapeutic effect of con- ventional decompressive craniectomy with hematoma evacuation and frame-based stereotactic minima......

miR-380-5p facilitates NRF2 and attenuates cerebral ischemia/reperfusion injury-induced neuronal cell death by directly targeting BACH1

期刊: TRANSLATIONAL NEUROSCIENCE, 2021; 12 (1)

Background This study aimed to explore the role of miR-380-5p in cerebral ischemia/reperfusion (CIR) injury induced neuronal cell death and the potent......

A new surgical method of treatment spontaneous intracranial hemorrhage

期刊: TRANSLATIONAL NEUROSCIENCE, 2021; 12 (1)

Objective. This study aimed to determine the safety and effectiveness of DTI-assisted neuroendoscopy for treating intracranial hemorrhage (ICH). Metho......

Dysregulated gene-associated biomarkers for Alzheimer's disease and aging

期刊: TRANSLATIONAL NEUROSCIENCE, 2021; 12 (1)

Alzheimer's disease (AD), the most common type of dementia, is a neurodegenerative disorder with a hidden onset, including difficult early detection a......

Immunoregulation and antidepressant effect of ketamine

期刊: TRANSLATIONAL NEUROSCIENCE, 2021; 12 (1)

Major depressive disorder (MDD) is a common mental health disorder that brings severe disease burden worldwide. Traditional antidepressants are mainly......

Chronic restraint stress impairs cognition via modulating HDAC2 expression

期刊: TRANSLATIONAL NEUROSCIENCE, 2021; 12 (1)

Background - To investigate the effects of chronic restraint stress on cognition and the probable molecular mechanism in mice. Methods - In the curren......

Nervonic acid amends motor disorder in a mouse model of Parkinson's disease

期刊: TRANSLATIONAL NEUROSCIENCE, 2021; 12 (1)

Objectives -Parkinson's disease (PD) is a kind of common neurodegenerative disease in the world. Previous studies have proved that nervonic acid (NA),......

Canstatin represses glioma growth by inhibiting formation of VM-like structures

期刊: TRANSLATIONAL NEUROSCIENCE, 2021; 12 (1)

Vasculogenic mimicry (VM) is different from classical tumor angiogenesis and does not depend on endothelial cells. VM is closely related to the progno......

Naringin attenuates cerebral ischemia-reperfusion injury in rats by inhibiting endoplasmic reticulum stress

期刊: TRANSLATIONAL NEUROSCIENCE, 2021; 12 (1)

Objective -This investigation was carried out with an aim of exploring neuroprotection by naringin (Nar) in rats with cerebral ischemia-reperfusion (C......

The potential antiepileptogenic effect of neuronal Cx36 gap junction channel blockage

期刊: TRANSLATIONAL NEUROSCIENCE, 2021; 12 (1)

Epilepsy is one of the most prevalent neurological disorders and can result in neuronal injury and degeneration. Consequently, research into new antie......

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