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A Systematic Review of Traditionally Used Herbs and Animal-Derived Products as Potential Analgesics

期刊: CURRENT NEUROPHARMACOLOGY, 2021; 19 (4)

Pain is a distressing but fundamental manifestation that prepares the body for potentially detrimental stimuli while ensuring its protection. Plant an......

Immune Checkpoint Inhibitors and Neurotoxicity

期刊: CURRENT NEUROPHARMACOLOGY, 2021; 19 (8)

Immune checkpoint inhibitors (ICIs) have recently been used as a promising treatment for cancer, while their toxicity and immune-related side effects ......

Src Family Kinases in the Central Nervous System: Their Emerging Role in Pathophysiology of Migraine and Neuropathic Pain

期刊: CURRENT NEUROPHARMACOLOGY, 2021; 19 (5)

Src family kinases (SFK) are a group of non-receptor tyrosine kinases which play a pivotal role in cellular responses and oncogenesis. Accumulating ev......

Pharmacological Strategy for Congenital Myasthenic Syndrome with CHRNE Mutations: A Meta-Analysis of Case Reports

期刊: CURRENT NEUROPHARMACOLOGY, 2021; 19 (5)

Background: Congenital myasthenic syndromes (CMSs) are a heterogeneous group of neuromuscular disorders. Mutations of the nicotinic acetylcholine rece......

The Management and Alternative Therapies for Comorbid Sleep Disorders in Epilepsy

期刊: CURRENT NEUROPHARMACOLOGY, 2021; 19 (8)

Background: There is a complex and interactive relationship between sleep and epilepsy. Sleep disorders are common in patients with epilepsy, and meth......

Gut Microbiota Regulate Astrocytic Functions in the Brain: Possible Therapeutic Consequences

期刊: CURRENT NEUROPHARMACOLOGY, 2021; 19 (8)

Astrocytes are essential for maintaining the homeostasis of the central nervous system (CNS). Astrocytic dysfunction has been implicated in the progre......

Progress and Promise of Nur77-based Therapeutics for Central Nervous System Disorders

期刊: CURRENT NEUROPHARMACOLOGY, 2021; 19 (4)

Nur77 belongs to the NR4A subgroup of the nuclear receptor superfamily. Unlike other nuclear receptors, a natural ligand for Nur77 has not been identi......

The Neuroprotective Role of Neuroserpin in Ischemic and Hemorrhagic Stroke

期刊: CURRENT NEUROPHARMACOLOGY, 2021; 19 (8)

Tissue plasminogen activator (tPA) is commonly used to treat acute ischemic stroke within an appropriate therapeutic window. Its inhibitor, neuroserpi......

Therapeutic and Mechanistic Effects of Curcumin in Huntington's Disease

期刊: CURRENT NEUROPHARMACOLOGY, 2021; 19 (7)

Curcumin is a spice derived nutraceutical which gained tremendous attention because of its profound medicinal values. It alters a number of molecular ......

Management Perspective of Wilson's Disease: Early Diagnosis and Individualized Therapy

期刊: CURRENT NEUROPHARMACOLOGY, 2021; 19 (4)

Wilson's disease (WD) is an inherited disease caused by mutations in ATP7B and is characterized by the pathological accumulation of copper in the live......

The Role of Autophagy in the Pathogenesis of Ischemic Stroke

期刊: CURRENT NEUROPHARMACOLOGY, 2021; 19 (5)

Autophagy is a strictly regulated process that degrades and recycles long-lived or mis-folded proteins and damaged organelles for the maintenance of e......

The Potentials of Uncariae Ramulus Cum Uncis for the Treatment of Mi-graine: Targeting CGRP in the Trigeminovascular System

期刊: CURRENT NEUROPHARMACOLOGY, 2021; 19 (7)

Migraine is a common chronic neurovascular disease characterized by headaches. Calci-tonin gene-related peptide (CGRP) signaling in the trigeminovascu......

Role of Hydrogen Sulfide and Polysulfides in Neurological Diseases: Focus on Protein S-Persulfidation

期刊: CURRENT NEUROPHARMACOLOGY, 2021; 19 (6)

Hydrogen sulfide (H2S) and hydrogen polysulfides are recognized as important signaling molecules that are generated physiologically in the body, inclu......

A Scientometrics Analysis and Visualization of Depressive Disorder

期刊: CURRENT NEUROPHARMACOLOGY, 2021; 19 (6)

Multiple studies on the pathomechanisms of depressive disorder and antidepressants have been reported. However, literature involving scientometric ana......

The Multifaceted Therapeutic Role of N-Acetylcysteine (NAC) in Disor-ders Characterized by Oxidative Stress

期刊: CURRENT NEUROPHARMACOLOGY, 2021; 19 (8)

Oxidative stress, which results in the damage of diverse biological molecules, is a ubiquitous cellular process implicated in the etiology of many ill......

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