期刊： JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2021; 31 (4)
This article not only presents a test based on the well-known Box M test for testing the equality of several covariance matrices with high-dimensional......
期刊： JOURNAL OF BIOPHARMACEUTICAL STATISTICS, ; ()
There has been limited research on the confidence intervals of the conditional odds ratio in matched-pairs design. This article investigates the inter......
期刊： JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2020; 30 (6)
The small n, Sequential, Multiple Assignment, Randomized Trial (snSMART) is a two-stage clinical trial design for rare diseases motivated by the compa......
期刊： JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2020; 30 (6)
Many Phase I trial designs have been developed to improve upon the standarddesign. These designs can be classified as long-memory designs, for example......
期刊： JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2020; 30 (6)
Adoptive cell therapy (ACT), such as chimeric antigen receptor (CAR) T-cell therapy, has demonstrated promising therapeutic effects with potentially n......
期刊： JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2020; 30 (4)
In recent years, subgroup analysis has emerged as an important tool to identify unknown subgroup memberships. However, subgroup analysis is still unde......
期刊： JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2019; 29 (3)
A stratified study is often designed for adjusting a confounding effect or effect of different centers/groups in two treatments or diagnostic tests, a......
期刊： JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2019; 29 (3)
Repeated measurements are widely encountered in medical or pharmaceutical studies, which can be analyzed by both longitudinal data and functional data......
期刊： JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 0; ()
The effect of reference treatment over placebo, known as M1, is essential in the development of non-inferiority margin. We proposed a M1 adjustment ap......
期刊： JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2019; 29 (1)
In stratified bilateral studies, responses from two paired body parts are correlated. Confidence intervals (CIs), which reveal various features of the......
期刊： JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2019; 29 (2)
In medical diagnostic research, medical tests with continuous values are widely employed to distinguish between diseased and non-diseased subjects. Th......
期刊： JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2019; 29 (4)
Personalized medicine has received increasing attentions among scientific communities in recent years. Because patients often have heterogenous respon......
期刊： JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2019; 29 (4)
For time-to-event outcomes, the Kaplan-Meier estimator is commonly used to estimate survival functions of treatment groups and to compute marginal tre......
期刊： JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2018; 28 (4)
The analysis and planning methods for competing risks model have been described in the literature in recent decades, and noninferiority clinical trial......
