Increased Retinal Ganglion Cell Survival by Exogenous IL-2 Depends on IL-10, Dopamine D1 Receptors, and Classical IL-2/IL-2R Signaling Pathways

Colares, TG; de Figueiredo, CS; Souza, LDJ; dos Santos, AA; Giestal-de-Araujo, E

Giestal-de-Araujo, E (corresponding author), Fed Fluminense Univ, Dept Neurobiol, Inst Biol, BR-24020150 Rio De Janeiro, Brazil.; Giestal-de-Araujo, E (corresponding author), Fundacao Oswaldo Cruz, Natl Inst Sci & Technol Neuroimmunomodulat INCT N, Inst Oswaldo Cruz, BR-21040360 Rio De Janeiro, Brazil.

NEUROCHEMICAL RESEARCH, 2021; 46 (7): 1701

Abstract

Interleukin-2 (IL-2) is a classical pro-inflammatory cytokine known to display neuroprotective roles in the central nervous system including the retin......

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