Blockade of IL-1α and IL-1β signaling by the anti-IL1RAP antibody nadunolimab (CAN04) mediates synergistic anti-tumor efficacy with chemotherapy

Millrud, CR; Deronic, A; Grönberg, C; Gyllenbäck, EJ; von Wachenfeldt, K; Forsberg, G; Liberg, D

Liberg, D (通讯作者),Cantargia AB, Ideon Gateway,Scheelevagen 27, S-22363 Lund, Sweden.

CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; 72 (3): 667

Abstract

IL-1 alpha and IL-1 beta are both involved in several aspects of tumor biology, including tumor initiation, progression, metastasis, and not least in ......

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