Rucaparib cocrystal: Improved solubility and bioavailability over camsylate

Xia, MY; Jiang, YH; Cheng, YX; Dai, WJ; Rong, XY; Zhu, BQ; Mei, XF

Zhu, BQ; Mei, XF (通讯作者),Chinese Acad Sci, Shanghai Inst Mat Med, Pharmaceut Analyt & Solid State Chem Res Ctr, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China.

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2023; 631 ():

Abstract

Rucaparib (Ruc) is a drug used to treat advanced ovarian cancer associated with deleterious BRCA mutations. Its commercial form, the camsylate salt (R......

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