RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML

Loke, J; Assi, SA; Imperato, MR; Ptasinska, A; Cauchy, P; Grabovska, Y; Soria, NM; Raghavan, M; Delwel, HR; Cockerill, PN; Heidenreich, O; Bonifer, C

Bonifer, C (reprint author), Univ Birmingham, Coll Med & Dent, Inst Canc & Genom Sci, Birmingham B15 2TT, W Midlands, England.

CELL REPORTS, 2017; 19 (8): 1654

Abstract

Acute myeloid leukemia (AML) is a heterogeneous disease caused by mutations in transcriptional regulator genes, but how different mutant regulators sh......

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