Sesquiterpene Lactones Potentiate Olaparib-Induced DNA Damage in p53 Wildtype Cancer Cells

Osborne, HC; Larrosa, I; Schmidt, CK

Schmidt, CK (通讯作者)，Univ Manchester, Sch Med Sci Med & Hlth, Manchester Canc Res Ctr MCRC, Div Canc Sci,Fac Biol, 555 Wilmslow Rd, Manchester M20 4GJ, Lancs, England.;Larrosa, I (通讯作者)，Univ Manchester, Dept Chem, Chem Bldg,Oxford Rd, Manchester M13 9PL, Lancs, England.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022; 23 (3):

Abstract

Despite notable advances in utilising PARP inhibitor monotherapy, many cancers are not PARP inhibitor-sensitive or develop treatment resistance. In th......

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