A DNA pool of FLT3-ITD positive DNA samples can be used efficiently for analytical evaluation of NGS-based FLT3-ITD quantitation - Testing several different ITD sequences and rates, simultaneously

Mezei, ZA; Tornai, D; Foldesi, R; Madar, L; Sumegi, A; Papp, M; Antal-Szalmas, P

Antal-Szalmas, P (reprint author), Univ Debrecen, Fac Med, Dept Lab Med, Nagyerdei Str 98, H-4032 Debrecen, Hungary.

JOURNAL OF BIOTECHNOLOGY, 2019; 303 (): 25

Abstract

Internal tandem duplication (ITD) in the fms-like tyrosine kinase 3 (FLT3) gene is one of the most frequent genetic alteration in acute myeloid leukem......

Full Text Link