Inhibition of Fatty Acid Synthase Upregulates Expression of CD36 to Sustain Proliferation of Colorectal Cancer Cells

Drury, J; Rychahou, PG; He, DH; Jafari, N; Wang, C; Lee, EY; Weiss, HL; Evers, BM; Zaytseva, YY

Zaytseva, YY (corresponding author), Univ Kentucky, Dept Toxicol & Canc Biol, Lexington, KY 40506 USA.; Zaytseva, YY (corresponding author), Univ Kentucky, Markey Canc Ctr, Lexington, KY 40506 USA.

FRONTIERS IN ONCOLOGY, 2020; 10 ():

Abstract

Fatty acid synthase, a key enzyme ofde novolipogenesis, is an attractive therapeutic target in cancer. The novel fatty acid synthase inhibitor, TVB-36......

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